OncoQR ML's Vaccine Platform Closes the Final Gap in the Immunological Attack Against Cancer

Scientific Breakthrough

By showing this, the Austrian Biotech is the first company* to succeed in controlling all the relevant immune checkpoints that prevent the immune system from attacking and defeating cancer.

Whereas current passive checkpoint specific immunotherapy lacks tumor cell specificity with the risk of massive autoimmune reactions, this new active therapy is totally tumor target specific.

Geert Mudde, PhD, inventor of the S-TIR™ technology and OncoQR’s Chief Scientific Officer, said, "We are proud and excited to have finally demonstrated the ability to activate and use the full potential of the patient’s own immune system to eradicate cancer. Previously, we had already shown all forms of antibody mediated tumor killing - now we have the definite proof that our S-TIR™ vaccines are able to simultaneously induce and activate tumor specific T Cell killing as well. With our approach, the tumor has no more chance to escape the immune system – it is attacked from all possible sides at the same time."

Economical Aspects

Christof Langer, Chief Executive Officer of OncoQR ML, said, "These spectacular results confirm the viability and huge potential of our proprietary S-TIR™ platform. Besides constituting a significant milestone in the development of our immunotherapy platform technology, to our knowledge, no other anti-cancer drug has shown comparable results so far. The new data are not only spectacular from a scientific point of view: The S-TIR technology will also break the trend that new cancer therapies have to be unethically expensive. Our therapeutic vaccines are designed to have low cost of goods which is paired with a personalized low treatment frequency at low treatment dose. Drugs based on our technology can be used as monotherapy but can also be combined with existing therapies (like chemotherapy). Therefore, all in all, ground-breaking news for patients, and healthcare organizations, but of course also for us and our future partners."

Out-Licensing Opportunity

With the achievement of this ultimate scientific proof, OncoQR ML’s S-TIR™ technology has now moved into the direct focus of different investors, and potential licensing and development partners: "Our Active Checkpoint Control Immunotherapy (ACCI) is available for out-licensing either as a whole or on a target-by-target basis. Developing S-TIR™ based vaccines for new cancer targets up to in vivo proof-of-concept typically only takes 6 to 9 months. Business partners, that are interested in truly enhancing the value of their current cancer immunotherapy product pipeline are warmly invited to contact us for additional information. This is not just another checkpoint inhibitor – it is a new, ground-breaking universal therapeutic approach."