Icagen Announces Collaboration with Bayer to Develop Novel XRpro® Assays

Icagen has announced a collaboration with Bayer to develop new X-ray fluorescence assays using the proprietary XRpro® platform.  These assays are designed to help Bayer to progress various early discovery programs in the area of transporter targets. 

A major obstacle for validation of transporters as targets and subsequent identification of molecules targeting transporters has been the lack of a broadly applicable high-throughput screening platform, especially for non-electrogenic transporters. To date, screening of non-electrogenic transporters in HTS mode can still be challenging and in certain cases is only achieved with indirect readouts. The XRpro® technology employs X-ray fluorescence as a method that enables a high throughput assessment of electrogenic and nonelectrogenic transporters, and is particularly well suited for certain classes of inorganic transporters.

"Icagen looks forward to collaborating with Bayer on this ground-breaking project," said Dr. Doug Krafte, Icagen's CSO.  "XRpro represents a unique application of X-ray fluorescence technology and has the potential to unlock new drug discovery efforts for previously untouched molecular targets."

The project has established key milestones and has the potential to span two years.