3D Cellular Models

Why not combine the best of both phenotypic and 3D approaches for drug discovery? There is a resurgence in using primary phenotypic screening strategies as a more productive approach over conventional target-directed methods. Three-dimensional cell culture recapitulates normal and pathological tissue architectures, thus providing physiologically relevant models to study normal development and disease. Challenges remain, though, for high-throughput screeners as researchers must procure large numbers of identical 3D cell cultures, develop assays and obtain fast, automated readouts from these more complex assays. Join cell biologists, tissue engineers, assay developers, screening managers and drug developers at Cambridge Healthtech Institute’s Inaugural 3D Cellular Models conference as they discuss strategies to accelerate the identification of novel therapeutic leads.

EYNOTE PRESENTATION: Integrating Multiple Organs-on-Chips: What Might We Learn, What Do We Need and How Might We Do It?

John P. Wikswo, Ph.D., Founding Director, Vanderbilt Institute for Integrative Biosystems Research and Education and Gordon A. Cain University Professor, Vanderbilt University