Where is the different place of medicinal auxiliary material oleic acid and oleic acid sodium?

What's the difference between the medical excipient oleic acid and sodium oleate do you know? Oleic acid and sodium oleate are commonly used as medical excipients. We believe that we will often come into contact with them in scientific research experiments. Both work with emulsifiers, but what is the difference between their physical and chemical properties? With AVT Xiaobian to know about it!

| Chinese name: oleic acid
| trade name: oleic acid (for injection)
| English name: Oleic acid (for injection)
| chemical name: cis - 9 - oleic acid
| English name: (Z) - Octadec - 9 - enoic acid
| molecular formula: C18H34O2
| manufacturers: YiWeiTa (Shanghai) pharmaceutical technology co., LTD
| the CAS no. : 112-80-1
| EINECS no. : 204-007-1
| and registration number: F20180000277
| levels: medicinal injection level
| purpose: emulsifier
| solubility: slightly soluble in water, easily soluble in ethanol, * *, * *, chloroform and methylene chloride
| purity: 70%
| molecular weight: 282.46
| preservation conditions: - below 15 ℃, the window closed
| note: avoid contact with alkaline, oxidizing substances
| article number: 004001
| Chinese name: sodium oleate
| trade name: Sodium oleic acid/Sodium Oleate
| chemical name: cis - 9 - oleic acid sodium salt
| molecular formula: C18H33O2Na
| manufacturers: YiWeiTa (Shanghai) pharmaceutical technology co., LTD
| the CAS no. : 143-19-1
| levels: medicinal injection level
| purity: soluble in water, slightly soluble in 90% ethanol
| purpose: emulsifier
| solubility: soluble in water, ethanol
| preservation conditions: - 18 ℃ below the window closed
| note: avoid contact with strong oxide
| article number: 004005

Oleic acid is generally extracted from plants. In addition to the main component, it often contains part of palmitic acid, linoleic acid and other fatty acids. The pure oleic acid should be a colorless, clear liquid. It will solidify into a soft solid at about 10℃ and will appear yellow due to impurities. Exposure to the air gradually darkens the color, and produces a series of oxidation products, light, high temperature can greatly accelerate the deterioration rate. Oleic acid is insoluble in water, but in ethanol, yi ether, chloroform and other organic solvents solubility is good, can be mixed in any proportion.

Sodium oleate is prepared by neutralizing the ethanolic solution of oleic acid with sodium hydroxide or sodium carbonate. White to light yellow solid at room temperature. Relative to oleic acid, sodium oleate solubility in water increases, can be dissolved in 10 times the amount of water, foaming, the formation of viscous liquid, due to partial hydrolysis into insoluble acid soap and sodium hydroxide, the solution is strongly alkaline, and become opacified. Soluble in about 20 times the amount of ethanol, almost insoluble in yi ether, petroleum ether and other organic solvents.

Oleic acid and sodium oleate are stored in different ways. Oleic acid is stored in a shaded and sealed environment below 15℃, while sodium oleate is stored in a shaded and sealed environment below -18℃. It's a distinction that needs to be noted.

AVT spot sale of high purity oleic acid (for injection), oleic acid, oleic acid sodium welcome to inquire: 400-6262-623!