What's the magic about functionalized PEG phospholipids DSPE-PEG2000-Mal?

What are functionalized PEG phospholipids? What is the role of functionalized PEG phospholipids? Functional PEG phospholipid DSPE- PEG2000-MAL is a functional PEG phospholipid. Follow the small series to understand it!

What are functionalized phospholipids?

In general, functional phospholipids are phospholipids that have nutritive and biological effects. As pharmaceutical excipients, functional phospholipids are phospholipids that can give drugs special properties such as targeting and intelligence.

What role do functional phospholipids play?

Phospholipids, used as medical excipients, have the functions of emulsification and drug solubilization. In recent years, they are important materials for the slow and controlled release of liposomes, fat emulsion, nanoparticles and other pharmaceutical preparations. By modifying the phospholipid molecules, these preparations can be released and targeted under specific conditions. The commonly used modification methods include: introducing polymer to improve the blood circulation time and disintegration time of the preparation; Introducing immune factors to enhance targeting; Markers were introduced for diagnosis and tracking.

Among them, polyethylene glycol (PEG) is a commonly used polymer to improve the performance of phospholipids, and its terminal can be further modified to connect polypeptides, nucleic acids and other ligands, so that PEG-phospholipid carrier has immune targeting, and the application in immune liposomes and other slow and controlled release preparations is currently the research focus of targeted drugs. We call this class of phospholipids functionalized PEG-phospholipids.

What's so great about functionalized PEG phospholipids DSPE-PEG2000-Mal?

At present, a variety of functional PEG-phospholipids have been commercialized, and the anti-swelling Liu drug preparation using this phospholipid has entered the clinical trial stage.

Functionalized PEG phospholipid DSPE-PEG2000-Mal is also an important member. This article introduces this phospholipid to our friends.

| Chinese name: two stearyl phosphatidyl acetamide - polyethylene glycol 2000 - maleic imide

| Chinese chemical name: 1, 2-2 stearoyl - SN - glycerol - 3 - phosphorus acyl ethanol amine - N - polyethylene glycol 2000 - maleic imide

| English name: DSPE - PEG2000 - Mal

| English chemical name: DSPE - Poly real (ethylene glycol) - Maleimide, business MW2000

| levels: reagents

| molecular weight: about 2890

| product features: white to white powder

| preservation conditions: - below 20 ℃, away from light

Functional PEG phospholipids include DSPE-PEG2000-MAL, one of the most important members of PEG2000-MAL. Contact us at 400-6262-623