What Is Thymopentin? Function And Application Range Of Thymopentin

Thymopentin is not common to us, because this drug is very serious for all diseases, such as malignant tumor patients and patients who have undergone major surgical treatment. They do not need to have a cold or fever at all. When it comes to thymopentin, there's no doubt that carbohydrates come to mind because thymopentin is made up of a variety of carbohydrates. What is the effect of thymopentin in severe diseases? How is it used?

Thymosin is composed of five carbohydrates: arginine, dicalcium phosphate, aspartic acid, valine and tryptophan. Its chemical name is n - [n - [n - [NL arginyl-l-lysine] - L - α - aspartyl] - l-valinyl] - L-tryptophan. Chemical equation: c30h49n9o9. Relative molecular weight: 679.77.

The active part of pancreatin II, a component of pancreas. Trypsin II is a single active peptide compound obtained from thymic hormone. It is composed of 49 kinds of carbohydrates. The wonderful peptide chain composed of five kinds of carbohydrates has all the same physiological functions as trypsin II. Therefore, this kind of pentapeptide wonderful fragment is called thymopentin. Milky white, dry frozen, loose in a small piece or powder.

Generally, thymopentin injection can be used for malignant tumor patients with immune function damage after radiotherapy and chemotherapy.

One of the functions of thymopentin is to induce T cell differentiation. In turn, it can induce the transformation of Thy-1 pancreatic cells into Thy-1 somatic cells. The high efficiency of T cell differentiation is mediated by the increase of intracellular cAMP level. Another basic function of thymopentin is to improve the binding of nonspecific protein kinases in peripheral blood t-somatic cells and increase the level of intracellular cAMP, which is also the basis of hormone regulation. 

Thymopentin has the effect of immune stimulation under all normal human standards. It can significantly enhance the formation rate and conversion rate of E-rosette of splenic reticulocyte, improve the different stages of the first or second reflex of immune response, and enhance the somatic cells of IgM species and IgG or IgA species that cause antigen. Thymopentin can also enhance the inflammatory mediators of macrophages, enhance the enzyme and inflammatory mediators for the counting of polymorphonuclear monocytes, enhance the antigen composition of the circulatory system, and enhance the immune function of blood cells. 

Thymosin can stimulate CD4 and CD8 positive cells, prolong the service life of nonspecific TC cells, and stimulate Th cells to induce the function of TS cells. The anti infectivity and efficacy of thymopentin are related to the nonspecific enhancement of tumor cells. In the aspect of anti infection immunity, appropriate thymopentin can continuously improve the production of interferon suppository. 

It can induce and promote the healthy differentiation of T cells, regulate the proportion of T lymphocyte subsets, and make CD4 / CD8 tend to normal. To improve the phagocytic ability of macrophages; to enhance the immune function of blood cells; to enhance the charm of destructive somatic cells; to enhance the level of interleukin-2 and protein kinase expression; to enhance the production of interferon suppository - γ suppository in peripheral blood mononuclear cells; to enhance the nonspecific SOD in blood cells.

It can be used for malignant tumor patients with immune function damage after radiotherapy and chemotherapy; the treatment of hepatitis B; the treatment of general surgery, severe, severe; immune system diseases, such as rheumatoid arthritis, lupus erythematosus; type II diabetes mellitus, female climacteric syndrome; the elderly, weak and sick, poor immune function.

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