Useful of Betadex sulfobutyl ether sodium

Product name: Betadex sulfobutyl ether sodium

Synonyms：Sulfobutyl Ether-β-cyclodextrin Sodium salt

CAS No.: 182410-00-0

DMF No.：030167

Standard : USP42

Grade: Injection grade

Molecular formula : C₄₂H_70-nO₃₅ (C₄H₈O₃S Na)n 

Molecular weight: 1135+158n

Packing:1kg/1bag,2kg/1bag, 10kg/drum or 20kg/1drum

 Application:

Only used in the medicine field. Especially anticancer drugs,such as Voriconazole,Posaconazole and

Delafloxacin.

1. Improve the stability of the drug, water solubility, safety

2. Reduce renal toxicity, ease drug hemolysis

3. Control the drug release rate, cover the bad smell

 Features:

Betadex sulfobutyl ether sodium(SBE-β-CD)is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.

 Betadex sulfobutyl ether sodium(SBE-β-CD)has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.