Use case and method of high purity injection grade cholesterol

In the last article, we took a close look at the basic situation of injection grade cholesterol medical auxiliary materials with purity up to 99%. In this period, Ai Weitao Xiaobian continues to introduce the application example of cholesterol to you.

1. Doxorubicin Liposome Injection (Doxil, 1995)

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Indications: Advanced ovarian AI, multiple myeloid *, and HIV complicated with Kaposi's sarcoma.

Cholesterol usage: injection method, dissolve in organic solvent together with phospholipids, under rapid stirring condition, slowly and uniformly inject appropriate concentration of ammonium sulfate solution.

2. Bupivacaine liposome injection (Exarel, 2011)

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Indications: postoperative local analgesia, upper limb surgery local anesthesia.

Cholesterol usage: dissolve in organic solvents with phospholipids, mix with water solution containing bupivacaine and emulsify to form colostrum under rapid shear condition.

Many large foreign R&D and production companies of GAO end injection, such as Gilead, Pacira, etc. have used refined cholesterol produced in Japan for more than ten years, and the products have been sold to the world. The quality and safety of the products can stand the test of the market, and they are worthy of trust!

In addition to these two use cases, there are many other use cases of high purity cholesterol such as amphotericin B liposome injection (AMB I Some, 1990). (Cholesterol usage: soluble in organic solvents with phospholipids and drugs, swirling and vacuuming for membrane preparation.)

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