The main role of Betadex sulfobutyl ether sodium in Medicine field

Cyclodextrin has a special ring hollow cylindrical structure with hydrophobic inner layer and hydrophilic outer layer. Cyclodextrin and its derivatives are mainly peptides and protein hormones, such as glucagon, salmon calcitonin, adrenocorticotropic hormone analogues, insulin, polypeptide Relin, luteinizing hormone and so on.

The main advantages of Betadex sulfobutyl ether sodium with negative charge as a new pharmaceutical excipient: because sulfobutyl beta cyclodextrin sodium has negative charge branched chain, it has special affinity and inclusion for nitrogen-containing drugs which are easy to form positive charge, which can better increase the solubility and stability of drugs, improve the bioavailability of drugs, and improve the release rate of drugs, It can reduce the irritation of drugs to local tissues, reduce the volatility of drugs, reduce toxic and side effects, cover up bad smell, and reduce nephrotoxicity.

The main function of Betadex sulfobutyl ether sodium used in injectable drugs is to improve the solubility of insoluble drugs, so that the drugs can be quickly delivered and reach the required dosage during injection, reduce the irritation of injection to the drug delivery site, improve the stability of drugs in solution state, alleviate the hemolysis of drugs, and improve the safety of drugs.

Betadex sulfobutyl ether sodium is widely used in the fields of injection, oral administration, nasal administration, eye administration, etc.

Shandong Binzhou Zhiyuan biological Co., Ltd. is a high-quality manufacturer of Betadex sulfobutyl ether sodium in China. Any inquiry. contact:+86 543-2616568