The Basic Principle Of Peptide Synthesis

Peptide solid phase synthesis is a major breakthrough in peptide synthesis chemistry. Its greatest feature is that it is not necessary to purify the intermediate product, and the synthesis process can be carried out continuously, which lays a foundation for the automation of peptide synthesis. At present, the synthesis of fully automatic peptides is basically solid phase synthesis. The basic process is as follows:

Based on Fmoc chemical synthesis, the carboxyl group of the C-terminal amino acid of the target peptide to be synthesized is first linked to an insoluble polymer resin by covalent bond, and then the amino group of this amino acid is used as a starting point for the synthesis of the peptide, together with other amino acids. The activated carboxyl group acts to form a peptide bond, and the process is repeated to obtain a peptide. Depending on the amino acid composition of the peptide, the post-treatment of the peptide is different and the purification methods are also different.

GT peptide is an expert at high-quality custom peptide synthesis for most biotech companies and academic institutes and consistently meets the highest standard of quality, customer service, and technical support. 

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