The 2023 CMC (Taizhou) Complex Formulation Industrialization Forum was successfully held!

On October 13th, the 2023 CMC (Taizhou) Complex Formulation Industrialization Forum was successfully held at the Wanyi Hotel in Taizhou.

This forum was jointly organized by the Management Office of Taizhou Pharmaceutical High tech Zone Pharmaceutical Industry Park, the Party Committee of Taizhou Pharmaceutical High tech Zone (Gaogang District) Biopharmaceutical Industry Alliance, in collaboration with Aiweituo (Shanghai) Pharmaceutical Technology Co., Ltd., Suzhou Aitesen Pharmaceutical Equipment Co., Ltd., Zhuhai OMAX Instrument Co., Ltd., and Shanghai Fluke Technology Development Co., Ltd.

Experts from the upstream and downstream of the pharmaceutical industry gathered together to deeply share and exchange ideas on the research and production difficulties, industry status, and development prospects of new complex formulations.

Forum Background

With the exploration and discovery of new molecular solid drugs becoming increasingly difficult, the research and development of nucleic acid drugs is becoming increasingly popular, the cost of investment in new drug research and development is also increasing, the risks encountered are increasing, and market competition is also becoming increasingly fierce. Currently, drug research and development has entered an era of high-tech and high barrier drug formulation innovation. Whether it is the special formulation of small molecule drugs, the delivery carrier of nucleic acid drugs, or the development of composite adjuvants for new vaccines, the research of new complex formulations has clearly become one of the hotspots of drug innovation.

Opening Speech

At the beginning of the conference, Li Wei, Deputy Director of the Management Committee of China Pharmaceutical City in Taizhou, Jiangsu, delivered a speech.

Fuming Zhang

R&D Director of Boji Pharmaceutical Technology Co., Ltd

A Brief Discussion on the Factors Influencing the Industrialization of Lipid System Agents from the Perspective of Industry, University and Research

From early research and development to later commercial production, combined with years of experience in research and development, production line construction, and application in the field of complex injections, we comprehensively explored the different considerations in the research and development process of liposome formulations.

li Gan

General Manager of Fubicheng (Shanghai) Pharmaceutical Technology Co., Ltd

Development Strategy for Improved New Drugs in Fat Emulsions

This article reviews the research and development history of fat emulsion formulations in China, focusing on the sub categories of complex formulations such as fat emulsion. It analyzes typical fat emulsion formulations such as aspirin and alprostadil, and emphasizes the key points in fat emulsion development strategies such as excipient screening, formulation technology upgrading, and the use of new auxiliary emulsifiers.

Weisan Pan

Professor of Pharmacy and Doctoral Supervisor at Shenyang Pharmaceutical University

Looking at the Development of Complex Formulations from Examples of Listed Products

Through multiple cases of complex formulations, the concept of complex formulations was first clarified, and the need for open thinking in the development of complex formulations was emphasized. The importance of supporting technologies, talents, and equipment and materials for the development of complex formulations was emphasized.

Changyou Zhan

Doctoral, second level professor and doctoral supervisor at Fudan University

Precise Regulation and Efficient Delivery of Lipid Nanocarriers

This article reviews the technological development from traditional liposomes to novel lipid nanoparticles (LNPs), focusing on the in vivo processes and regulatory mechanisms of lipid nanoparticles. It introduces the latest research progress of lipid nanoparticles as drug delivery systems to achieve precise regulation and efficient delivery, bringing new thinking to the research and development of new lipid nanoparticles formulations.

Jiayong Tong

Product Director of Suzhou Aitesen Pharmaceutical Equipment Co., Ltd

From Lab to Production: CMC Challenges and Core Process Equipment Analysis for Micro and Nano Formulations

Introduced the main links and quality control throughout the liposome process, analyzed core process equipment such as high-pressure homogenizers, and shared practical experience in continuous manufacturing and linear amplification of micro and nano formulations.

Xingzhi Shen

Product Manager of Zhuhai OMAX Instrument Co., Ltd

Application of Nanoparticle Size and Zeta Potential Analysis Detection Technology in Quality Evaluation of Pharmaceutical Preparations

This article introduces the analysis principle and testing method of dynamic light scattering nanoparticle size and electrophoretic light scattering Zeta potential, and combines specific cases such as liposome vaccine adjuvants to introduce the application of relevant detection equipment in pharmaceutical formulation optimization and quality control.

Kailei Yu

Product Director of Shanghai Fluke Technology Development Co., Ltd

Introduction to the Application of High Shear Technology in Micro and Nano Formulations

Introduced the application of fluid power equipment in the process of mixing, homogenization, emulsification, dispersion, and other processes in the field of complex formulation pre-treatment, and shared relevant experience of linear amplification in the pre-treatment process of complex formulations.

Onstage Question

In the on-site interactive segment, the attending guests answered the audience's questions, creating a strong academic atmosphere.

Next, Aiweituo will travel to more cities across the country to continue organizing city forums related to the field of high-end preparations, and explore various forms of special activities, including technical seminars, theoretical training, practical exercises, etc., to assist in the industrialization of high-end preparations from multiple perspectives and promote the development of the high-end preparation industry. We look forward to your attention and participation!