Sodium hyaluronate HA-SHL with a variety of uses

n this article, I will introduce sodium hyaluronate/sodium hyaluronate HA-SHL (used as bone and joint injection, eye drops, surgical anti-adhesion products and ophthalmic viscoelastic agents, etc.) in the form of video.


| Chinese name: sodium hyaluronate/sodium hyaluronate

| trade name: HA - SHL

| chemical name: poly (beta - glucuronic acid - [1-3] - beta n-acetyl glucosamine - [1-4])

| English chemical name: Poly real (beta - glucuronic acid - [1-3] - beta - N - acetylglucosamine - [1-4]), alternating

| molecular formula: (C14H20NNaO11) n

| manufacturer: Japan chobe co., LTD

| the CAS no. : 9067-32-7

| DMF number: 33346

| EINECS no. : 232-678-0

| and registration number: Y20180000263

| levels: medicinal injection level

| executive standard: enterprise standard

The indicators | purity: 99.8% (see COA)

| application: can be used as a joint injection, eye drops, and adhesion products, and an eye surgery viscoelastic agent, etc

| solubility: dissolved in water, in the yi alcohol, ketone of bin or yi hardly soluble in ether

| molecular weight: 150 ~ 3.9 million

| preservation conditions: below 15 ℃

| note: avoid coexist with strong acid, strong alkali, strong oxide


Application in ophthalmic surgery

High molecular hyaluronic acid is usually used as viscoelastic agent in ophthalmic surgery. With its good viscoelasticity and poor fluidity, it can be used as a gel to support the anterior chamber, providing a clear vision for the operation and reducing the damage to the cornea. At the same time, hyaluronic acid gel can compress the bleeding point, play a molecular blocking role in the movement, proliferation, differentiation and phagocytosis of Yi cells, and reduce the occurrence of postoperative inflammation.

Application of eye drops

Hyaluronic acid is the best and safest media in eye preparations at present, it can not only play its own hydrating and moisturizing effect in the eye, relieve eye dryness, but also increase the biological availability of drugs, reduce the stimulation of drugs on the eye, promote the healing of eye wounds, and quickly relieve the symptoms of discomfort.

Drug sustained-release effect: the hydrophilic group in HA molecule interacts with mucin, which can delay the elimination of drugs and improve bioavailability. Physical viscosification can increase the drug retention time in vivo to improve the efficacy. Spreading and wetting ability: HA can effectively prolong the tear film rupture time, lubricate and protect the eyeball, relieve dryness of the eye and protect the cornea. HA is a safe and effective drug for curing xerophthalmia. It is also a safe and effective viscosifier in many eye drops.

Today hyaluronic acid is used more and more widely. As a giant in R&D and production of hyaluronic acid, Japan's century-old enterprise Chubby Co., Ltd. has a wide variety of products and excellent quality, and is the world's largest raw material supplier. AVT, as its sole JIA agent in China, sells all kinds of hyaluronic acid products produced by Chobe, and the medical grade has been registered in CFDA, which can be used by major domestic scientific research institutes and pharmaceutical enterprises. Welcome to call our 400 number for consultation: 400-6262-623