Shandong Binzhou Zhiyuan Biotechnology picks up the gauntlet to fight coronavirus

Shandong Binzhou Zhiyuan Biotechnology is leading manufacturer located in Binzhou City, Shandong Province,China, and is involved in the fight against coronavirus via its expertise in the cyclodextrin technology and by manufacturing the critical excipient, Dexolve (sulfobutyl-ether beta-cyclodextrin, SBECD) that enables remdesivir to work. SBECD is combined with a wide range of active pharmaceutical ingredients to improve their solubility or stability. Remdesivir, which is a broad-acting antiviral with tremendous efficacy, is practically insoluble in water, which prevents the preparation of an injectable formulation to treat patients. Once pharma companies (Gilead and numerous others globally) use the proper technology and combine the active with this particular cyclodextrin, remdesivir gets water-soluble, can exert its effect and fight the virus effectively.