Precautions for use of Dierucylphosphatidylcholine DEPC (DMF No. 19577)

This AVT editor gives you an introduction to a medicinal phospholipid - dierucoyl phosphatidylcholine DEPC, engage in scientific research partners to DEPC this phospholipid products should not be unfamiliar with it.Dierucylphosphatidylcholine is widely used in liposomes. What are the precautions for the use of erucylphosphatidylcholine DEPC?

What kind of phospholipid product is Dierucylphosphatidylcholine DEPC?

Product name: Dierucylphosphatidylcholine (for injection)

Common name: DEPC

Chemical name: 1,2-Dierucoyl-sn-glycero-3-phosphocholine

CAS Number: 51779-95-4

Registration Number: F20180000839

DMF number: 19577

Grade: medicinal injection grade

Molecular weight: 898.35

Molecular formula: C52H100NO8P

Product characteristics: white powder

Solubility: easily soluble in chloroform, methanol, ethanol; insoluble in acetone and water

Applicable fields: liposome membrane material, emulsifier

Storage conditions: below -20℃, shading and airtight

Dierucylphosphatidylcholine DEPC application case introduction

Speaking of the application of Dierucylphosphatidylcholine DEPC, do you know Exparel? It's a liposome injection of bupivacaine.Indications: Postoperative analgesia.

DEPC Phospholipid Usage:

Secondary emulsification method, dissolved in chloroform together with other phospholipid excipients, uniformly mixed with bupivacaine aqueous solution under high-speed shearing conditions, emulsified to form W/O structure, and continued to be evenly mixed with appropriate buffer solution under high-speed shearing conditions , emulsify to form W/O/W structure colostrum, and then perform subsequent purification and other operations.

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