Inclusion of retinol with sulfobutyl beta cyclodextrin sodium

Retinol is fat soluble, which is an essential factor to regulate the growth and health of epithelial cells. It can thin the surface of rough and aging skin and promote the normalization of cell metabolism. It is an eye care product with obvious wrinkle removing effect. It can be used in wrinkle removing, whitening and other advanced cosmetics. Retinol also helps cells reproduce and differentiate from necrotic cells, and as an antioxidant, it binds to free radicals that can produce gene mutations. Retinol is also widely known in the cosmetics industry because of its remarkable anti-aging and anti wrinkle effects. But because it is very sensitive to light, heat, high price metal ions, poor stability, easy to cause skin allergy and other factors, it has not been widely used in the cosmetics industry.

Betadex Sulfobutyl Ether Sodium has a special structure of "hydrophobic inner cavity and hydrophilic outer wall", and its characteristics are very stable. It is not easy to be affected by pH, enzyme, heat and other external conditions. Hydrophobic inner cavity can provide an ideal site for its interaction with hydrophobic guests of certain size and shape (such as organic molecules, inorganic ions, biological small molecules, complexes and even inert gases) In order to change the physical and chemical properties of guest molecules, play the role of shielding, controlled release, activity protection, and expand the application field of guest molecules.

The sustained-release and high-efficiency product of retinol encapsulated by Betadex Sulfobutyl Ether Sodium improves the bioavailability of retinol, is conducive to skin absorption, and can also be water-soluble. This product not only has all the effects of retinol, can effectively prevent and reduce fine wrinkles, reduce skin roughness, reduce color spots, but also has more stability and safety.