November 12, 2020
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Gout is an inflammation. Due to the disorder of purine metabolism, the concentration of uric acid in human blood is too high, resulting in excessive reaction of immune system and pain. Most of the cases were located in the toes, fingers and knees. Most of them are middle-aged men aged 30-50 years old, and only 5% of them are women. In recent years, gout patients are becoming younger.
Usually, uric acid is excreted from the urine through the kidney. But if there's too much purine, uric acid builds up in the body. When the concentration of uric acid reaches a certain concentration, uric acid crystallizes out. Crystals produced at the joints can cause gout. Gout usually begins with the big toe or the back of the foot and gradually spreads to other joints.
Purine is a substance existing in human body, which plays an important role in energy supply, metabolic regulation and coenzyme composition.
The new functional material anserine can effectively control uric acid.
1. It can inhibit the formation of uric acid.
HPRT enzyme (hypoxanthine phosphoribosyltransferase) is a kind of reutilization enzyme, which can increase the quantity of HPRT enzyme and make purine return to purine state before it is decomposed into uric acid, so as to inhibit the excessive production of uric acid.
2. It can help the excretion of uric acid and reduce the content of uric acid.
Due to excessive drinking and fatigue, lactic acid accumulates too much in the body, which hinders the excretion of uric acid. Goose carnosine can increase the LDH (lactate dehydrogenase) of lactate metabolism, reduce the competitive inhibition of uric acid excretion by renal tubules by promoting the metabolism of lactic acid in vivo, so as to achieve the effect of excreting uric acid.
If uric acid is compared to "water in a water tank", carnosine is a "water regulating device". Adjust the concentration of uric acid, drain water in time, and keep the water level of uric acid storage tank.
The results of the study on decreasing uric acid by carnosine.
Serum uric acid levels (6.5 ~ 8.0 mg / dl) were divided into two groups. One group was given goose carnosine capsules (50mg daily) and the other group was given placebo capsules. The medication lasted for 4 weeks.
The results showed that the uric acid value of the people taking goose carnosine decreased after two weeks compared with that before taking goose carnosine. In addition, during the two weeks after taking the medicine, the uric acid value also decreased significantly compared with that before treatment.
Compared with the placebo group, the psychological response was also improved as shown in the figure. The curve of serum uric acid decreased significantly in the group taking carnosine than that in the group taking carnosine.
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