Exploring Dry Powder Inhalers (DPIs)

Dry Powder Inhalers (DPIs) represent a significant advancement in respiratory treatment, offering a convenient and effective method for delivering medication directly to the lungs. Unlike traditional inhalers that rely on propellants or pressurized gases, DPIs use the patient's own breath to disperse a fine powder formulation of medication.

The design of DPIs is engineered to ensure precise dosing and ease of use. They typically consist of a reservoir containing the powdered medication, a mechanism to break up the powder into tiny particles, and a mouthpiece through which the patient inhales. This process allows the medication to reach deep into the lungs where it can be rapidly absorbed, providing quick relief for conditions such as asthma, chronic obstructive pulmonary disease (COPD), and other respiratory ailments.

One of the key advantages of DPIs is their portability and simplicity. They do not require coordination between pressing a canister and inhaling, making them suitable for patients of all ages, including children and the elderly.

In clinical practice, DPIs have demonstrated efficacy in improving patient adherence to prescribed therapies and reducing the frequency of respiratory exacerbations. They offer healthcare providers a reliable option for managing chronic respiratory conditions with minimal side effects and maximum patient comfort. Moreover, DPIs are often preferred for their environmental friendliness, as they do not release harmful propellants into the atmosphere.

Bona has our own research on DPI devices. We use “R”(Airflow Block) to evaluate the performance of the DPI, kPa 0.5/L/min.

R: Airflow Block, kPa 0.5/L/min; Q: Flow, L/min; ∆P: Pressure drop, kPa.

At present, BONA’s DPI have 3 specifications: 0.017 kPa0.5/L/min, 0.039kPa0.5/L/min, 0.058kPa0.5/L/min(Q=60L/min). It can also be customized according to different requirements.