March 27, 2023
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Citrus aurantium is the dried young fruit of the sour or sweet orange and its cultivars in the family Rutaceae. The shape is hemispherical, a few are spherical, the color of the outer pericarp is black-green or dark brown-green, with granular protrusions and wrinkles, with obvious stigma remnants or fruit pedicel marks. The peel is slightly elevated in the cut surface, yellowish white or yellowish brown or sac brown. The odor is fresh, bitter and slightly sour in taste.
Citrus aurantium extract has strong pharmacological effects. Some experiments have shown that it has a two-way regulatory effect on the smooth muscle function of the gastrointestinal tract, which can both excite the gastrointestinal tract and enhance intestinal peristalsis, and reduce intestinal smooth muscle tone and relieve spasm. The aqueous decoction of Citrus aurantium by gavage can stimulate gastric smooth muscle and inhibit isolated intestinal smooth muscle, significantly reducing its tone and inhibiting contraction. The product has an inhibitory effect on intestinal smooth muscle at low concentrations, while at high concentrations it first briefly inhibits intestinal smooth muscle and then manifests an excitatory effect.
A related study showed that its aqueous decoction had a significant excitatory effect on rabbit uterus in vitro or in vivo, pregnant or non-pregnant uterus. Contractility and tone were increased, and even tonic contractions were observed. The alkaloids contained in Citrus aurantium have a contractile effect on the uterus of rabbits, and the removal of these alkaloids causes relaxation of the uterus, which has a moderating effect on the uterus.
Citrus aurantium extract can reduce the painful reaction of patients caused by acetic acid and can reduce the increase of body temperature caused by rabbit typhoid vaccine. In addition to the above effects, Citrus aurantium extract also has vasoprotective, analgesic and antipyretic, and diuretic effects.
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