August 05, 2021
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HSPC hydrogenated soybean phosphatidylcholine as a commonly used semi-synthetic phosphatidylcholine, I believe you will not be unfamiliar, this article let AVT xiaobian to explain the specific application of HSPC hydrogenated soybean phosphatidylcholine!
1. Amphotericin B liposome Injection (Ambisome, 1990)
composition
|
AmB |
HSPC |
DSPG |
CHO |
: |
1 |
5 |
2 |
2.5 |
mg |
50mg |
213mg |
84mg |
52mg |
Indications: severe depth ****.
HSPC usage: Dissolve in appropriate organic solvent with phospholipid and medicine, steam in water bath at 55℃, vacuum to make film.
2. Doxorubicin Liposome Injection (Doxil, 1995)
|
AmB |
HSPC |
DSPG |
CHO |
|
17 |
56 |
39 |
5 |
mg/m'l |
2mg/mL |
9.58mg/mL |
3.19mg/mL |
3.19mg/mL |
Indications: advanced ovarian *, multiple bone marrow *, and KAPosi's sarcoma with HIV.
HSPC usage: Dissolve in appropriate organic solvent with phospholipid, slowly and uniformly inject into water solution containing polyxorubicin under the condition of 55℃ water bath and rapid stirring to form uniform colostum.
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