October 31, 2020
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The β-cyclodextrin can be gelled in a specific solvent environment to form a single gel factor β-cyclodextrin gel and a multi-gel factor β-cyclodextrin gel. External factors have a significant effect on the formation of β-cyclodextrin organic small molecule gel. Temperature, host molecules, guest molecules, solvents and metal ions can affect the formation of β-cyclodextrin gel. The β-cyclodextrin organic small molecule gel is a typical supramolecular gel and thus exhibits good stimuli responsiveness to external stimuli. Temperature changes, metal ions and acid can lead to β-cyclodextrin gel. Dissociation.
Beta-cyclodextrin is a cylindrical truncated cone structure, which is hydrophilic outside the cavity and hydrophobic in the cavity. It can encapsulate some hydrophobic guest molecules, thus achieving the transport of hydrophobic drug molecules. The solvent of the β-cyclodextrin organic small molecule gel can also carry hydrophilic drug molecules, and thus the β-cyclodextrin organic small molecule gel can achieve dual carrying of hydrophobic drug molecules and hydrophilic drug molecules.
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