Application of Cyclodextrin derivatives in Cosmetics

Cyclodextrin derivatives can be divided into water soluble, oil soluble and iononic. Water-soluble cyclodextrin derivatives include branched chain cyclodextrine, methylated cyclodextrin, hydroxyethyl cyclodextrin, hydroxypropyl cyclodextrin, low molecular weight β-cyclodextrin polymer (molecular weight of 3000-6000), etc. Oil-soluble cyclodextrin derivatives products include ethylcyclodextrin, acetyl cyclodextrin, etc. Ionic cyclodextrin derivatives include nitrogen-containing cationic products and anionic products, and anionic products such as carboxymethyl cyclodextrin. The main roles in cosmetics are as follows:

1. Because the object molecules are wholly or partially covered in the molecular hole, they can maintain a certain degree of isolation from the peripheral environment, effectively preventing the oxidation and degradation of the object molecules.

2. Because such coating effectively hinders the natural decomposition process of the coated active substance, it better extends the action time of the active substance.

3. has certain coated active objects, presenting control release properties, which help improve the bioavailability of active objects.

4. can significantly improve or enhance the activity of some active components.

5. Since the coating process is reversible and the final covering complex is crystalline, it is not susceptible to compressive stress.

6. effectively improves the odor and appearance of the product by coating the unpleasant gas molecules and components with color problems.In addition, since cyclodextrin itself has the ability to cover the unpleasant volatile components secreted by the human body, it can serve as an active ingredient of deodorant products.

7. Due to the stability and solubility properties of cyclodextrin and its derivatives, it can effectively reduce the amount of surfactant in the product, further reduce the stimulation of the skin, and improve the safety of the product.

8. reduces moisture absorption of components or products.