A method to improve the stability and water solubility of resveratrol

Resveratrol (resveratrol) is a polyphenolic antitoxin mainly found in grape, peanut, Polygonum cuspidatum and other plants. It has anti-inflammatory, antibacterial, anti-oxidation, anti-cancer, regulating blood lipid and other biological activities.The hydroxypropyl β- cyclodextrin is soluble in water, and the solubility is more than 50%(m/V) at room temperature, or even more than 75%(m/V) at room temperature. Therefore, it can not crystallize in alcohol aqueous solution, when its concentration is less than 40%, the fluidity is good and not sticky.Hydroxypropyl β- cyclodextrin can increase the solubility and bioavailability of insoluble drugs.

massage er ratio 1∶1~2 encapsulate resveratrol molecules in hydroxypropyl-β- cyclodextrin at 2030℃, then freeze-dried to prepare resveratrol microcapsules, the product appearance is white powder, tasteless, easy to dissolve in water (not less than 7 mg/ml at room temperature), stability significantly improved, conducive to broaden the application of resveratrol in daily chemical, health food and pharmaceutical fields. The water or emulsion with anti-oxidation and anti-aging was prepared by adding the microencapsulation to cosmetics products in a certain proportion.a certain proportion of resveratrol microcapsule was added to juice beverage or fruit wine, and mixed well, and the juice beverage or fruit wine with anti-cardiovascular disease, anti-oxidation and other health effects was prepared. the resveratrol containing 1~200 mg per 100 ml beverage or fruit wine.