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[CAS Name] Venlafaxine

[Formula] C17H28N2O

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[CAS Name]Venlafaxine
[Alias](?-1-[a-[(dimethylamino)methyl]-p-methoxybenzyl]cyclohexanol; N,N-dimethyl-2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethylamine; venlafexine; 1-[2-(dimethylamino)-1-[4-(methylamino)phenyl]ethyl]cyclohexanol
[Number]93413-69-5
[EINECS]
[Formula]C17H28N2O
[Molecular weight]276.417

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Shanghai Wonder Pharmaceutical Co.,Ltd.

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Suzhou Hengyi Pharmaceutical Co.,Ltd

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Jinan Jianfeng Chemical Co., Ltd.

Venlafaxine Usage And Synthesis

Chemical Properties	White Solid
Uses	A optically active version of Venlafaxine, a selective serotonin noradrenaline reuptake inhibitor. Used as an antidepressant
Uses	antidepressant;serotonin-norepinephrine reuptake inhibitor
Definition	ChEBI: A tertiary amino compound that is N,N-dimethylethanamine substituted at position 1 by a 1-hydroxycyclohexyl and 4-methoxyphenyl group.
Brand name	Effexor (Wyeth).
Biological Functions	Venlafaxine (Effexor) inhibits the reuptake of both serotonin and norepinephrine at their respective presynaptic sites.This drug does not have significant effects at muscarinic, histamine, or α-adrenergic receptors and therefore is devoid of many of the side effects associated with the TCAs.Venlafaxine and its active metabolite O-desmethyl-venlafaxine, have half lives of 5 and 11 hours respectively, so dosing twice a day is necessary. However, an extended release preparation (Effexor XR) now allows for once-daily dosing and better tolerance. Venlafaxine has a side effect profile similar to that of the SSRIs. Higher doses of venlafaxine result in modest increases in blood pressure in approximately 5% of patients.Venlafaxine has minimal effects on the cytochrome P450 enzyme system.

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