Cas no for 53714-56-0,Leuprorelin ACID Cas number search msds database,online free cas number chemistry search engine,cas number sigma aldrich

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Home > CAS No. Inquiry > 53714-56-0

53714-56-0

[CAS Name] Leuprorelin

[Formula] C59H84N16O12

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Basica Info

[CAS Name]Leuprorelin
[Alias]Leuprolide; (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-GNRH; (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-LHRH; (D-Leu(sup 6),des-gly-NH2(sup 10),pro-ethylamide(sup 9))-gonadotropin-releasing hormone; A-43818; CCRIS 8462; Eligard; HSDB 6518; Leuprorelina; Leuprorelina [INN-Spanish]; Leuproreline; Leuproreline [INN-French]; Leuprorelinum; Leuprorelinum [INN-Latin]; NSC 377526; UNII-EFY6W0M8TG; Luteinizing hormone-releasing factor (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-; Luteinizing hormone-releasing hormone (pig), 6-D-leucine-9-(N-ethyl-L-prolinamide)-10-deglycinamide-; 5-oxoprolyl-L-histidyl-L-tryptophylseryl-L-tyrosyl-D-valyl-L-valyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide acetate (1:1); 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-N~5~-(diaminomethylidene)-L-ornithyl-N-ethyl-L-prolinamide
[Number]53714-56-0
[EINECS]
[Formula]C59H84N16O12
[Molecular weight]1209.3983

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HYBIO PHARMACEUTICAL CO., LTD.

Indications:

Advanced prostate cancer
Endometriosis
Central precocious puberty
Uterine fibroids
Some cases of infertility

Mechanism of Action: Leuprorelin acts as an agonist at pituitary GnRH receptors. With continuous administration, it initially stimulates the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). However, with chronic use, it suppresses these hormones, leading to decreased testosterone in males and decreased estrogen in females.

Pharmacokinetics:

Absorption: Depends on the formulation. Long-acting forms are developed to slowly release the drug.
Distribution: Distributed widely in the body.
Metabolism: Minimal metabolism, with the majority of the drug remaining intact.
Excretion: Excreted primarily through the kidneys.

Form: Leuprorelin API is usually available as a white to off-white powder.

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AFINE CHEMICALS LIMITED

Standard or custom package excellent quality and reliable supplier

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Ningbo distant chemicals co.,ltd

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