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Sinoway Industrial Co.Ltd.
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Product name
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(-)-Corey Lactone P-Phenylbenzoate alcohol ; BPCOD
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CAS No.
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31752-99-5
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Molecular Formula
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C8H12O4
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Grade Standard
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Medical grade
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Appearance
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White to off-white crystalline powder
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COA of (-)-Corey Lactone P-Phenylbenzoate alcohol
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ITEM
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SPECIFICATION
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RESULTS
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Appearance
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Off-white to white crystalline powder
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White crystalline powder
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Identification
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IR spectrum of sample complies with the Reference Spectrum
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Complies
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m.p.
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130.0 - 135.0℃
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133.5-134.0℃
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Purity (by HPLC)
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> 99%
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99.68%
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Chiral Purity (by HPLC)
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> 99%
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100.00%
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· Prostaglandin intermediate, is a building block for the preparation of an analog of PGF2 [alpha], a potent and selective anti-glaucoma drug.
· As prostaglandins can cause strong contraction of the uterus, it is applied to full-term pregnancy induced abortion, abortion and contraception, and achieved some results. Prostaglandin treatment of asthma, gastrointestinal ulcer disease, shock, hypertension and cardiovascular disease may have a certain effect, which aroused people's attention.
· The main physiological function of PG PGE2 can induce inflammation, promote local vasodilatation, increased capillary permeability, causing red, swollen, pain, fever and other symptoms. PGE2, PGA2 make arterial smooth muscle relaxation, lower blood pressure. PGE2 and PGI2 inhibit gastric acid secretion, promote gastrointestinal smooth muscle motility. Follicles produce PGE2 and PGF2α play an important role in ovulation. PGF2α can ovarian smooth muscle contraction, causing ovulation. Uterine release of PGF2α luteal lysis. PGF2α released from the endometrium during childbirth can cause contractions of the uterus to be strengthened and promote childbirth. |
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Sinoway Industrial Co.Ltd.
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Product name
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(-)-Corey Lactone Diol 32233-40-2
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CAS No.
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32233-40-2
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Molecular Formula
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C8H12O4
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Molecular Weight
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172.20
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Quality Standard
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98% up by HPLC
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Appearance
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White powder
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COA of (-)-Corey Lactone Diol
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Function of Prostaglandins (PGs)
(-)-Corey Lactone Diol is one of important Prostaglandins (PGs) intermediates.
Prostaglandins (PGs) are a series of compounds with a wide range of physiological activities. Natural prostaglandins (prostaglandins, hereinafter referred to as PG) are a series of compounds with a wide range of physiological activities. Natural PGs have relatively few sources and mainly exist in marine coelenterates, certain higher plants, mammals and humans. But the content is very small. A large number of studies have proved that although the content of PGs in various tissues of the human body is very small, they all have quite obvious physiological activities. The central nervous system, reproductive system, etc. have important roles. At the same time, the causes of many diseases have an important relationship with the imbalance of endogenous PGs. Because endogenous natural products are inherent to the human body, PGs are less toxic to the human body, so they have a wide range of uses in the field of medicine. Through the efforts of medical workers in recent decades, PGs derivatives have successfully become an important class of drugs. They are mainly used for lowering blood pressure, regulating menstruation, anti-early pregnancy, anti-blood coagulation, induction of labor, induction of labor, anti-tumor, anti-inflammatory, and anti- Viruses, hypnosis, treatment of asthma, glaucoma, constipation and gastric ulcer disease. In addition, PGs also have important applications in animal husbandry. Therefore, PGs have attracted widespread attention in the fields of chemistry, pharmacy, medicine and biology. |
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Pharma Sources Insight January 2025
