Factory Supply 99% Synthetic Lanreotide acetate Powder CAS NO 108736-35-2
Introduciton:
Lanutide is a drug used to treat acromegaly and a syndrome caused by neuroendocrine tumors. It is similar to octreotide, a long-acting somatostatin analogue
Lanreotide is a synthetic cyclic octapeptide analogue of somatostatin. Lanreotide binds to somatostatin receptors (SSTR), specifically SSTR-2 and also to SSTR-5 with a lesser affinity. However, compare with octreotide, this agent is less potent in inhibiting the release of growth hormone from the pituitary gland. Furthermore, lanreotide has an acute effect on decreasing circulating total and free insulin-like growth factor 1 (IGF-I). This agent is usually given as a prolonged-release microparticle or Autogel formulation for the treatment of acromegaly and to relieve the symptoms of neuroendocrine tumors.
Lanreotide is a synthetic polypeptide analogue of somatostatin that resembles the native hormone in its ability to suppress levels and activity of growth hormone, insulin, glucagon and many other gastrointestinal peptides. Because its half-life is longer than somatostatin, lanreotide can be used clinically to treat neuroendocrine tumors that secrete excessive amounts of growth hormone (acromegaly) or other active hormones or neuropeptides. Lanreotide has many side effects including suppression of gall bladder contractility and bile production, and maintenance therapy may cause cholelithiasis and pancreatitis as well accompanying liver injury
Fuction & Application:
Lancretin can be used in biological studies for statistical structural alarm of furans, phenols, nitrosoarenes and thiophenes. Can be used for peptide synthesis. It's an analogue of a natural growth hormone statin peptide. It's a physiological inhibitor of the growth hormone. Lanreotide also has antitumor effects.
Certificate of Analysis
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Product Name
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Lanreotide acetate Powder(Synthetic)
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Batch No.
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191228
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Sequence: {D-2Nal}-Cys-Tyr-{D-Trp}-Lys-Val-Cys-Thr-NH2(Cys2&Cys7bridge)， CAS:127984-74-1，
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Mfg. Date
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Dec 24, 2019
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Exp. Date
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Dec 23, 2021
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Items
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Specifications
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Results
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Appearance
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White or off-white powder
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Conforms
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Solubility
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Soluble in H2O
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Conforms
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Related Substances
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Unspecified impurity for each impurity:NMT1.0%
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0.1%(single largest impurity)
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Purity (HPLC)
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NLT 98.0%
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99.9%
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Acetic acid
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NMT13.0%
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11.9%
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Peptide Content (N%)
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NLT 80%
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83.6%
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Water Content (KarlFischer）
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NMT 8.0%
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4.0%
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Mass spectrum
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1096.3±1.0
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1096.0
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Storage: In an air tight container, protected from light at temperature 2-8℃. Conclusion: the product complies with enterprise standard.
Not for human use without further Sterile processing.
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