HYBIO PHARMACEUTICAL CO., LTD.
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Indications:
- Improvement of glycemic control in adults with type 2 diabetes mellitus.
- Treatment of adults with obesity or overweight, having weight-related comorbidities or complications.
Mechanism of Action: Liraglutide mimics the action of the endogenous hormone GLP-1, which enhances glucose-dependent insulin secretion, suppresses inappropriate glucagon secretion, delays gastric emptying, and reduces appetite and food intake.
Pharmacokinetics:
- Absorption: Subcutaneously administered, with peak plasma concentrations achieved in 11 hours.
- Distribution: Vd approximates 20-25 L.
- Metabolism: Metabolized via endogenous pathways similarly to large proteins without a specific organ as a major route of elimination.
- Excretion: Mainly through feces.
Form: Liraglutide API is typically found as a clear and colorless solution or as a white lyophilized powder. |
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