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Powder Flow: Particle Size-independent Variation of Bulk Excipients
Tim Freeman
August 12, 2019
Microcrystalline Cellulose (MCC) has been used as a pharmaceutical excipient for many years, due to its abundance, ease of production and resistance to degradation.
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Powder Flow: The Influence of Roller Compactor Process Parameters on Granule Properties
Tim Freeman
July 17, 2019
Dry granulation by roller compaction is a continuous process applied routinely to convert fine, difficult to handle powders into uniform granular products that flow freely and perform efficiently in subsequent manufacturing steps.
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Powder Flow: The Influence of Storage and Handling
Tim Freeman
June 26, 2019
When working with powders, in-process performance and final product quality will be influenced by properties of the raw materials delivered to the process.
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Powder Flow: The Influence of Particle Size and Shape on Flow Properties
Tim Freeman
April 17, 2019
The size and shape of the particles within a powder are important factors in influencing behaviour, and many well-established techniques exist for measuring these properties.
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Powder Flow: Batch Variability in spray coating Applications
Tim Freeman
March 08, 2019
In spray coating applications, a fine powder, typically a polymer, is drawn from a storage device before being fluidised and ejected through a charged nozzle onto a substrate.
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Powder Flow: Developing a Design Space for a Die Filling Operation
Tim Freeman
February 19, 2019
Filling is a common operation across all industries, although fill weights and tolerances vary widely.
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Powder Flow and Powder Testing: Capsule Filling
Tim Freeman
January 14, 2019
In the pharmaceutical industry, the blending of a small fraction of active pharmaceutical ingredient (API) with a bulk excipient, and then subsequent processing though various unit operations, is an essential part of many manufacturing processes.
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Powder Testing and Powder Flow: Applications of the FT4 in Additive Manufacturing
Tim Freeman
December 21, 2018
Additive manufacturing, also known as 3D printing, is a potentially transformative, highly efficient manufacturing technique.
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Powder Flow: Powder characterization for formulators
Tim Freeman
November 30, 2018
Accelerating product development through formulation into successful manufacture and on to the market place, is an important goal for the pharmaceutical industry.
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Powder Flow: Powder characterization for process designers and engineers
Tim Freeman
November 15, 2018
For process designers specifying new plant, the goal is to engineer equipment that will process and handle powders consistently and efficiently, as defined by the design brief.