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Initiating Empirical Tx for Sepsis Reduces Blood Culture Sensitivity
drugs
September 18, 2019
When empirical antimicrobial therapy is initiated in patients with severe manifestations of sepsis, the sensitivity of blood cultures drawn shortly after treatment initiation is reduced...
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Combo Antithrombotic Therapy Increases Bleeding Risk
drugs
September 18, 2019
Patients with chronic coronary artery disease or peripheral artery disease treated with the combination of rivaroxaban and aspirin face a greater risk for bleeding versus patients treated with aspirin alone...
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Physical Therapy and Surgery Reduce Mixed Urinary Incontinence Symptoms
drugs
September 18, 2019
In women with mixed urinary incontinence, symptom reduction is significantly greater when behavioral and pelvic floor muscle therapy is combined with midurethral sling surgery compared with surgery alone ...
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Scottish Medicines Consortium approves Kymriah® CAR-T therapy
europeanpharmaceuticalreview
September 12, 2019
The Kymriah (tisagenlecleucel) treatment has received a positive appraisal from the Scottish Medicines Consortium, after EMA approval last year.
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Metastatic NSCLC therapy, tepotinib, given Breakthrough Designation
europeanpharmaceuticalreview
September 12, 2019
Tepotinib, an investigational therapy for patients with metastatic non-small cell lung cancer has been given Breakthrough Therapy Designation.
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Age Modifies Effects of Estrogen Therapy in Women Without Ovaries
drugs
September 12, 2019
For women aged 50 to 79 years, the effects of conjugated equine estrogens (CEE) do not differ according to bilateral salpingo-oophorectomy (BSO) status...
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CAR T for Large Tumors: The Next Frontier?
contractpharma
September 12, 2019
Traditional cancer treatments tend to be unprecise, the effect of which both healthy and cancerous cells are destroyed. Chemotherapy or radiation are like the military carpet bombing an area...
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Ridgeback Biotherapeutics Breakthrough Therapy Designation for mAb114
americanpharmaceuticalreview
September 10, 2019
Ridgeback Biotherapeutics announced the Food and Drug Administration (FDA) has recently granted mAb114, an experimental treatment for Ebola, Breakthrough Therapy designation.
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Alternative viral delivery of gene therapy developed
europeanpharmaceuticalreview
September 10, 2019
New nanocapsules are a promising platform for many types of gene therapies due to their small size and superior stability.
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HRT Could Benefit Younger Women After Hysterectomy
drugs
September 10, 2019
Estrogen therapy may help younger women live longer after having their uterus and ovaries surgically removed, new research reports.