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The human brain contains large quantities of the small alpha-synuclein protein. Its exact biological function is still unknown, yet it is closely linked to Parkinson's disease; the protein "clumps together" in the nerve cells of Parkinson patients.
The FDA approved Newron Pharmaceuticals, Zambon and US WorldMeds' Xadago (safinamide) as an add-on therapy to levodopa/carbidopa for patients with Parkinson's disease, the companies announced Tuesday.
Acorda Therapeutics' experimental drug CVT-301 demonstrated a significant improvement in motor function versus placebo in people with Parkinson's disease experiencing OFF periods in a Phase III study, the company reported.