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MHRA green light for DemeRx’s opioid use disorder trial pharmatimes
March 11, 2021
The UK Medicines and Healthcare products Regulatory Agency (MHRA) has approved the launch of a Phase I/IIa trial of DemeRx and atai Life Sciences’ ibogaine HCl (DMX-1002) for the treatment of opioid use disorder (OUD).
Breaking the Cycle of Opioid Addiction: Alar Presents Positive Interim Results of Long-acting Buprenorphine Injectable (ALA-1000) in Opioid Dependent Patients prnasia
March 10, 2021
Alar Pharmaceuticals Inc., a clinical-stage biopharmaceutical company focused on developing long-acting injectables (LAIs) for central nervous system disorders, announces positive interim results from the single-ascending-dose study of ALA-1000.
Purdue Pharma pleads guilty to three criminal charges pharmaceutical-technology
November 26, 2020
Opioid maker Purdue Pharma has pleaded guilty in federal court in Newark, New Jersey, to criminal charges over the handling of its OxyContin painkiller drug.
Drug used to treat opioid addiction can reverse some adverse events caused by type 2 diabetes: Study expresspharma
November 04, 2020
IIT Mandi researchers find that low-dose naltrexone (LDN) can activate SIRT1, a critical protein molecule, thereby reducing inflammation and increasing insulin sensitivity of cells.
Novel non-opioid postsurgical pain implant launched europeanpharmaceuticalreview
November 02, 2020
Innocoll Holdings Limited has announced the commercial launch of the XARACOLL® (bupivacaine HCI) implant, a non-opioid treatment for acute post-surgical pain for up to 24 hours in adults following open inguinal hernia repair.
Purdue Pharma reaches agreement with DOJ over opioid medicines pharmaceutical-technology
October 23, 2020
Purdue Pharma has reached an $8.3bn settlement agreement with the United States Department of Justice (DOJ) to resolve multi-year civil and criminal investigations into its past marketing practices related to its opioid medicines.
DOJ Announces Deal with Purdue Pharma, Civil Settlement with Sackler Family americanpharmaceuticalreview
October 22, 2020
The Department of Justice (DOJ) has announced a global resolution of its criminal and civil investigations into the opioid manufacturer Purdue Pharma, and a civil resolution of its civil investigation into individual shareholders from the Sackler family.
Mallinckrodt files for bankruptcy to resolve opioid claims pharmaceutical-technology
October 14, 2020
Mallinckrodt has initiated Chapter 11 proceedings in the US Bankruptcy Court for the District of Delaware to modify its capital structure, reduce debt and settle opioid claims.
Global opioid use disorder market to reach $3.7 bn by 2028: GlobalData expresspharma
September 27, 2020
The main driver of growth will be the launch of reformulations of buprenorphine, in particular, extended-release formulations.
J&J faces $2bn insurance fraud charges over opioid claims pharmaceutical-technology
September 21, 2020
The New York State Department of Financial Services (DFS) has filed a $2bn lawsuit against Johnson & Johnson (J&J) for its alleged role in the opioid crisis in the US.

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