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Novartis' oral therapy iptacopan shows promise in PNH
pharmatimes
June 16, 2021
Novartis has revealed new positive data for its investigational treatment iptacopan as a monotherapy treatment for patients with the rare blood disorder paroxysmal nocturnal hemoglobinuria (PNH).
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Rafael Holdings Announces Appointments to its Board of Directors
firstwordpharma
June 15, 2021
Rafael Holdings, Inc., (NYSE: RFL), today announced the appointment of three senior biopharmaceutical leaders to its Board of Directors: Ameet Mallik, Chief Executive Officer of Rafael Holdings; Shannon Thyme Klinger, Chief Legal Officer of Moderna, Inc..
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Novartis Announces Iptacopan Met Primary Endpoint in Rare Kidney Disease IgA Nephropathy
americanpharmaceuticalreview
June 09, 2021
Novartis announced Phase II primary endpoint data showing investigational iptacopan (LNP023) – a first-in-class, oral, targeted factor B inhibitor – reduced protein in the urine (proteinuria), an increasingly recognized surrogate marker correlating ...
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Novartis Tislelizumab Meets Primary Endpoint of Overall Survival in Esophageal Cancer
americanpharmaceuticalreview
June 08, 2021
Novartis announced results from the pivotal Phase III RATIONALE 302 trial showing the investigational anti-PD-1 immune checkpoint inhibitor tislelizumab improved overall survival (OS) versus chemotherapy (median 8.6 months vs. 6.3 months, p=0.0001).
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Novartis’ CAR T therapy Kymriah shows promise in follicular lymphoma
pharmatimes
June 04, 2021
Novartis’ CAR T therapy Kymriah has shown promise for the treatment of relapsed or refractory follicular lymphoma – the second most common form of non-Hodgkin lymphoma (NHL).
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Novartis reports 'clinically relevant' survival data for Lutathera
pharmatimes
June 04, 2021
Novartis has reported findings of a final analysis of data from the Phase III Netter trial, showing that its radioligand therapy Lutathera (INN: lutetium (177Lu) oxodotreotide / USAN: lutetium Lu 177 dotatate) extended overall survival in patients ...
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Novartis Presents Positive Results from JUNIPERA Study Supporting Cosentyx as a Treatment in a JIA Population
americanpharmaceuticalreview
June 04, 2021
Novartis, a leader in rheumatology and immuno-dermatology, announced 2-year positive results from the Phase III JUNIPERA study, demonstrating that Cosentyx® (secukinumab) significantly delayed time to flare vs placebo (P<.001) in pediatric patients ...
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FDA Approves Novartis Cosentyx for Children with Plaque Psoriasis
americanpharmaceuticalreview
June 04, 2021
Novartis, a leader in immuno-dermatology and rheumatology, announced that the FDA has approved Cosentyx® (secukinumab) for the treatment of moderate to severe plaque psoriasis in pediatric patients six years and older who are candidates for systemic ...
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Cosentyx approved to treat plaque psoriasis in paediatric patients
pharmatimes
June 03, 2021
The US Food and Drug Administration (FDA) has approved Novartis’ interleukin-17A (IL-17A) inhibitor Cosentyx for the treatment of children and adolescents with moderate to severe plaque psoriasis.
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Novartis and Molecular Partners commence Covid-19 treatment trial
pharmaceutical-technology
May 31, 2021
Novartis and Molecular Partners have commenced Phase II/III EMPATHY clinical trial of a new DARPin therapeutic candidate, ensovibep (MP0420), to treat Covid-19.