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IL-18 inhibitor drug holds great potential for inflammatory diseases
europeanpharmaceuticalreview
April 26, 2019
An international team of researchers has identified the key role that IL-18 protein plays in Still’s disease, making it a prime candidate for IL-18 inhibitor drug that is proving promising in current trials.
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AACR: Bayer posts early clinical data on follow-up to Loxo's Vitrakvi
fiercebiotech
April 03, 2019
Bayer has shared preliminary clinical data on the second TRK inhibitor it licensed from Loxo Oncology.
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CStone received IND approval in China for HDAC6 inhibitor CS3003
en-cphi.cn
March 13, 2019
Cstone announced that the National Medical Products Administration (NMPA) recently approved company's histone deacetylase 6 (HDAC6) selective inhibitor CS3003 for Phase I clinical trial in China.
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Groundbreaking Memory Research Shows Amazonian Plant Extract PTI-00703 Cat's Claw as Potent Inhibitor and Reducer of Both Brain Plaques and Tangles
en-cphi.cn
March 06, 2019
Scientific Reports recently published a landmark research paper which has immediate favorable implications for brain health and memory loss in the aging brain.
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Morphic and Janssen collaboratively develop integrin therapies
pharmaceutical-technology
February 26, 2019
Biotechnology company Morphic Therapeutic has formed a research and collaboration alliance with Johnson & Johnson subsidiary Janssen for the discovery and development of new integrin therapeutics....
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Innovent and Incyte Announce Strategic Collaboration and Licensing Agreement for Three Clinical-stage Product Candidates in China
pharmafocusasia
December 17, 2018
Innovent Biologics, Inc. and Incyte today announced that the companies, through their respective subsidiaries, have entered into a strategic collaboration agreement for .....
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Rodin Therapeutics Announces Initiation of Phase 1 Clinical Trial of a Selective CoREST Inhibitor to Treat Neurologic Diseases
pharmafocusasia
December 13, 2018
Rodin Therapeutics today announced the initiation of a Phase 1 clinical trial of the company’s lead candidate, RDN-929, a potent and selective HDAC-CoREST inhibitor.
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GlaxoSmithKline to buy Tesaro for $5.1 billion, gaining PARP inhibitor Zejula
firstwordpharma
December 03, 2018
GlaxoSmithKline announced Monday an agreement to acquire Tesaro for around $5.1 billion in cash, gaining the latter's oral PARP inhibitor Zejula (niraparib). GlaxoSmithKline CEO Emma Walmsley said the deal "will strengthen our pharmaceuticals business by
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CStone’s MEK inhibitor approved for trials in China
pharmaceutical-technology
August 01, 2018
CStone Pharmaceuticals has announced its CS3006, a small molecule inhibitor of mitogen-activated protein kinase (MEK), has received investigational new drug approval for clinical trials from the China National Drug Administration (CNDA). This comes only t
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Bristol-Myers posts early checkpoint combination data on fast-advancing rival to Incyte’s IDO1 inhib
fiercebiotech
November 13, 2017
Bristol-Myers Squibb has posted interim data on its IDO1 inhibitor in combination with Opdivo.