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'Own' immune cells to target infectious diseases including COVID-19
worldpharmanews
April 26, 2020
The engineering of specific virus-targeting receptors onto a patient's own immune cells is now being explored by scientists from Duke-NUS Medical School (Duke-NUS).
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AstraZeneca and Saint Luke’s Mid America Heart Institute initiate Phase III DARE-19 trial with Farxiga in COVID-19 patients
worldpharmanews
April 26, 2020
AstraZeneca and Saint Luke's Mid America Heart Institute have initiated a randomised, global Phase III trial to assess the potential of Farxiga (dapagliflozin).
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Key nose cells identified as likely COVID-19 virus entry points
worldpharmanews
April 26, 2020
Two specific cell types in the nose have been identified as likely initial infection points for COVID-19 coronavirus. Scientists discovered that goblet and ciliated cells in the nose have high levels of the entry proteins that the COVID-19 virus uses to g
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FDA reiterates importance of close patient supervision for 'off-label' use of antimalarial drugs
worldpharmanews
April 26, 2020
The U.S. Food and Drug Administration issued a Drug Safety Communication regarding known side effects of hydroxychloroquine and chloroquine, including serious and potentially life-threatening heart rhythm problems.
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HVP Launches Global Initiative to Accelerate the Development of COVID-19 Vaccines
americanpharmaceuticalreview
April 26, 2020
The Human Vaccines Project (HVP), a global nonprofit consortium, is launching the COVID Vaccine Initiative (CVI) to develop safe, effective, accessible vaccines for those most vulnerable to COVID-19.
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CMIC Supports Avigan Production for Potential COVID-19 Treatment
contractpharma
April 26, 2020
Includes clinical trials and manufacturing of influenza antiviral drug for COVID-19 patients.
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FDA Cautions Use of Hydroxychloroquine, Chloroquine for COVID-19 Outside Hospital Due
americanpharmaceuticalrevie
April 26, 2020
The FDA is aware of reports of serious heart rhythm problems in patients with COVID-19 treated with hydroxychloroquine or chloroquine, often in combination with azithromycin and other QT prolonging medicines. We are also aware of increased use of these me
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Cytovance and Akshaya Enter Vaccine Collaboration
contractpharma
April 26, 2020
Partnership to focus on therapeutics for treatment of coronavirus and hepatitis B virus infections.
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Gilead says leaked Covid-19 trial data of remdesivir inconclusive
Pharmaceutical-Technology.
April 26, 2020
Gilead’s remdesivir has failed to show benefit in a clinical trial conducted to treat Covid-19 patients in China, according to data the World Health Organization (WHO) accidentally posted on its website.
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J&J selects Emergent BioSolutions for Covid-19 vaccine manufacturing
pharmaceutical-technology
April 26, 2020
Johnson & Johnson (J&J) subsidiary Janssen Pharmaceutical has signed an agreement with Emergent BioSolutions for manufacturing services for its lead investigational Covid-19 vaccine candidate.