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Gilead, Novartis tout long-term data for CAR-T slow starters Yescarta, Kymriah
fiercepharma
December 05, 2018
Gilead and Novartis are working to ramp up launches of their slow-starting CAR-T drugs, and both companies are hoping longer-term follow-up data will help do the trick.
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Sartorius and Immunochina Partner to Advance Immunotherapy Development
pharmafocusasia
December 04, 2018
Sartorius Stedim Biotech (SSB), a leading international supplier of the biopharmaceutical industry, through its China affiliate, and Beijing-based Immunochina Pharmaceuticals....
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CAR-T cell update: Therapy improves outcomes for patients with B-cell lymphoma
worldpharmanews
December 04, 2018
In their phase-2 study of tisagenlecleucel (marketed as KYMRIAH®), to be published on-line Dec. 1, 2018 in the New England Journal of Medicine, an international team of researchers evaluated 93 patients with relapsed or refractory diffuse large B-cell lym
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First children set to receive Novartis’ Kymriah
pharmatimes
November 28, 2018
The first children to receive Novartis’ Kymriah – a ‘game-changing’ CAR-T therapy for cancer - will start treatment at Great Ormond Street Hospital in London this week, NHS England has announced.
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Novartis focusing on cutting CAR-T costs ahead of EU launches
pharmaphorum
November 26, 2018
Novartis is focusing on cutting manufacturing costs for its CAR-T cancer cell therapy as the company launches it across Europe, while keeping a watching brief on ‘off-the-shelf’ therapies that could potentially be cheaper to produce.
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20 year old man died after leukaemia cell was accidently mixed into CAR T therapy
pharmafile
November 20, 2018
A 20 year old man died after a single leukaemia cell accidentally ended up in a batch of cells that were being manufactured into a CAR-T cell therapy, according to researchers at the University of Pennsylvania.
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F1 Oncology Expands Operations
contractpharma
November 18, 2018
Shanghai EXUMA will develop these clinical programs into multicenter trials under a centralized regulatory pathway based on the results of investigator-initiated trials (IITs) of CAR-T therapies for the treatment of metastatic renal cell carcinoma (mRCC)
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F1 Oncology Expands Operations
contractpharma
November 18, 2018
Shanghai EXUMA will develop these clinical programs into multicenter trials under a centralized regulatory pathway based on the results of investigator-initiated trials (IITs) of CAR-T therapies for the treatment of metastatic renal cell carcinoma (mRCC)
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Calithera compound empowers immuno-oncology therapies by targeting metabolic signals
fiercebiotech
November 02, 2018
Can targeting one metabolic signaling pathway have completely opposite effects on different subsets of T cells? In the case of glutamine metabolism, the answer seems to be ...
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England's cost watchdogs nix Novartis' Kymriah for adults
fiercepharma
September 30, 2018
Cost watchdogs in England turned away Kymriah in adults with relapsed or refractory diffuse large B-cell lymphoma after two prior therapies.