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Leukine® is beneficial to patients with mild-to-moderate Alzheimer’s, finds study
europeanpharmaceuticalreview
March 26, 2021
In a Phase II trial, Leukine® (sargramostim) significantly reduced biomarkers of neurodegeneration and improved cognitive function.
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Salbutamol significantly increases cerebral perfusion in proof-of-concept trial
europeanpharmaceuticalreview
March 17, 2021
In the Phase I trial, the beta-2 adrenoceptor agonist salbutamol significantly increased cerebral perfusion, a key biomarker in neurodegenerative disease.
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Cassava Sciences Enters Drug Supply Agreement with Evonik
contractpharma
March 10, 2021
Evonik will supply Cassava Sciences with large-scale, clinical-grade quantities of simufilam.
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Oxford University to develop Alzheimer’s disease treatments with Exscientia
pharmatimes
February 22, 2021
The Alzheimer’s Research UK Oxford Drug Discovery Institute (ARUK-ODDI) has announced a partnership with AI drug discovery company Exscientia on the development of therapies for Alzheimer’s disease.
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XPro1595 significantly improves neurodegeneration in AD trial
europeanpharmaceuticalreview
January 26, 2021
Treatment with XPro1595 for three months caused significant changes in neurodegeneration, synaptic function and neuroinflammation.
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US approves Chinese drug maker Shanghai Green Valley’s Alzheimer’s therapy for large-scale clinical trials
SCMP
April 27, 2020
A Chinese drug maker has received approval from the Food and Drug Administration to start clinical trials in the US for a breakthrough Alzheimer’s drug as it seeks global validation for the controversial therapy.
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Eisai Continues Alzheimer's Research, Adds 2 Alzheimer's Pros as Execs
biospace
May 05, 2019
The industry was shaken up when Tokyo-based Eisai and its collaboration partner, Biogen, announced they were abandoning huge swaths of their Alzheimer’s program related to aducanumab in late March.
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AbbVie and Mission partner on Alzheimer’s and Parkinson’s drugs
pharmaceutical-technology
November 20, 2018
AbbVie has collaborated with UK-based drug discovery firm Mission Therapeutics for research and preclinical development of potential therapies to treat Alzheimer’s disease and Parkinson’s disease.
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Pain Therapeutics hit with yet another CRL, plots ‘reorganization,’ Alzheimer’s pivot
fiercebiotech
August 07, 2018
With little surprise, Pain Therapeutics has been hit with a complete response letter from the FDA for Remoxy ER, its extended-release, capsule gel form of the opioid oxycodone.
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Brain’s lymphatic system, just recently discovered, now linked to aging and Alzheimer’s
fiercepharma
July 30, 2018
The accumulation of amyloid-beta in the brain is believed to be a culprit behind neurodegeneration, but the underlying mechanism of the buildup is not yet clear.