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Finding of dementia genes could speed drug discovery in Alzheimer’s and other brain disorders
fiercebiotech
January 02, 2019
The overproduction of a protein called tau has long been observed in the neuron degeneration that causes Alzheimer’s and other forms of dementia. But the exact genetic process that causes tau to proliferate has been something of a mystery.....
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Eisai, UCL extend neuro pact, gear up for Alzheimer’s phase 1
fiercebiotech
December 28, 2018
Six years after Eisai and University College London teamed up to discover new treatments for neurological diseases, they are moving their first candidate into the clinic.....
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Lilly pays AC Immune $81M upfront for preclinical Alzheimer’s drug
fiercebiotech
December 27, 2018
Eli Lilly has paid CHF 80 million ($81 million) upfront for the worldwide rights to AC Immune’s tau aggregation inhibitors in Alzheimer’s disease.....
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Tetra, Shionogi ink $40M pact on PDE4 drug for Alzheimer’s, fragile X
fiercebiotech
December 25, 2018
Tetra Discovery Partners is teaming up with Shionogi to advance its PDE4-targeting drug in Alzheimer’s disease and fragile X syndrome......
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Roivant wins $200m backing to expand R&D operations
pharmaphorum
December 03, 2018
Biotech startup Roivant has won a further $200 million backing from investors in a financing round valuing the company at $7 billion.
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Liver disease drug could help restore cells damaged by Alzheimer’s
financialexpress
September 07, 2018
New study found ursodeoxycholic acid (UDCA) improves mitochondrial dysfunction – which is known to be a causative factor for both sporadic and familial Alzheimer’s disease
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Eye Disease Link to Alzheimer's Seen
drugs
August 13, 2018
Researchers have discovered a link between three degenerative eye diseases and Alzheimer's disease.
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vTv reports Alzheimer’s candidate failure
pharmatimes
July 17, 2018
It is looking likely that another late-stage candidate for Alzheimer’s disease will fail to make it past Phase III trials, with vTv Therapeutics’ experimental therapy the latest in a long line to miss its targets.
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Biogen and Eisai’s previously bleak Alzheimer’s study comes back with positive results
fiercebiotech
July 09, 2018
A phase 2 Alzheimer’s trial—once nearly consigned to the heap of disappointing attempts against the disease—has re-emerged with new positive results
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Alzheimer's breakthrough: Brain metals that may drive disease progression revealed
worldpharmanews
July 05, 2018
Alzheimer's disease could be better treated, thanks to a breakthrough discovery of the properties of the metals in the brain involved in the progression of the neurodegenerative condition, by an international research collaboration including the Universit