Specification of Analysis
| Product Name |
Lafutidine Powder |
| CAS |
118288-08-7 |
| Appearance |
white powder |
| Molecular formula |
C22H29N3O4S |
| Molecular Weight |
431.55 |
| Assay |
98% |
| Shelf Life |
Two years |
| Storage |
Store in a dry, cool and sealed place |
What is Lafutidine?
Lafutidine (INN) is a second generation H2 receptor antagonist having multimodal mechanism of action. It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not only suppresses gastric acid secretion, but also has cytoprotective properties by the virtue of its property to induce the collagen synthesis in the gastric mucosa. It has a novel mechanism of action in addition to blocking the H2 receptors, it decreases inflammation by modulating calcitonin gene-related peptide (CGRP) and vanilloid receptors It is also found to stimulate mucin biosynthesis and promote the restitution of damaged mucosa.
Function and Application of Lafutidine
Lafutidine (INN) is a second generation H2 receptor antagonist having multimodal mechanism of action.
It is currently marketed in Japan (Stogar) China (Lemeiting) and India (Lafaxid) It not only suppresses gastric
acid secretion, but also has cytoprotective properties by the virtue of its property to induce the collagen
synthesis in the gastric mucosa. It has a novel mechanism of action in addition to blocking the H2 receptors,
it decreases inflammation by modulating calcitonin gene-related peptide (CGRP) and vanilloid receptors It
is also found to stimulate mucin biosynthesis and promote the restitution of damaged mucosa. |
Pharma Sources Insight June 2024: Globalization on the Go
