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Beijing Global Biologicals Co.Ltd
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Aminoglycoside antibiotic G418 108321-42-2 litol 72432-03-2
Specification:
G418 (Geneticin) is an aminoglycoside antibiotic similar in structure to gentamicin B1. It is produced by Micromonospora rhodorangea. G418 is produced by fermentation and isolation processes and the G418 producing strainMicromonospora rhodorangea produces many other gentamycins while producing G418. The common impurities of G418 include gentamycin X2, gentamicin A, gentamycin C1, C2, C1a and C2a. The quality of G418 is not based on just the potency, but more on the selectivity defined by the killing curve of the sensitive cells vs the resistant cells. A good G418 product has the lowest LD50 for sensitive cells (such as NIH 3T3) and the highest LD50 (can be up to 5,000 μg/ml) for resistant cells (NIH 3T3 transfected with resistant genes). Gentamycins have almost no selectivity, except gentamycin X2.
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Beijing Global Biologicals Co.Ltd
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Description
Geneticin (G418) Sulfate is an aminoglycoside antibiotic that has originally been derived from Micromonospora rhodoranga NRRL 5326. This compound has been shown to cause a bypass of nonsense mutations during translation. Experiments have shown that geneticin sulfate inhibits the incorporation of amino acids into protein and can destroy fibroblasts. Mechanistic studies suggest that this agent affects the 80S ribosome and inhibits the elongation cycle. Further studies report that geneticin sulfate is highly active against amoebae, protozoa, tapeworm, and pinworm exposed murine cells.
Usage
• Potency: ≥700 μg/mg
Technical Information
| Appearance: |
Powder |
| Physical State: |
Solid |
| Solubility: |
Soluble in water (50 mg/ml) and aqueous buffers. |
| Storage: |
Store at 4° C |
| Boiling Point: |
1012.1 °C at 760 mmHg (Predicted) |
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Seebio Biotech (Shanghai) Co., Ltd.
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Fructo oligosaccharides (FOS) is a mixture of oligosaccharides (GF2, GF3, GF4) which are composed of fructose units connected by ß (2-1) links. These molecules are terminated by a fructose unit. The total number of fructose or glucose units (Degree of Polymerization or DP) of oligofructose ranges mainly between 2 and 4.
Fructose oligosaccharides(FOS), is also know as Fructo-oligo, it directly enters into large intestine without being digested and absorbed by human body, and in intestine it rapidly promotes reproduction of bididobactirium and other probiotics, so it is also called “Bifidus Factor”.
This product is an excellent prebiotic and soluble dietary fiber as well. It can improve bowel function, prevent constipation and diarrhea. Currently it has been widely used in food, health products and other industries.
Properties
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Product:
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Fructo oligosaccharide (FOS) |
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Grade:
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Food grade,95%
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Synonym:
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Fructooligosaccharide; oligofructose; oligofructan |
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Systematic IUPAC name:
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- |
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Product No.:
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catalog number |
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CAS No.:
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308066-66-2 |
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Formula:
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- |
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Mol. Weight:
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- |
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Melting Point:
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- |
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Specific rotation:
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- |
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Density:
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- |
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Solubility:
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N/A |
Specifications
| Fructo oligosaccharide (FOS), [308066-66-2] |
| Item |
Value |
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| Content of Fructo-oligosaccharide |
95.0% min |
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Content of glucose, fructose and sucrose
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5% max
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| pH |
4.5 - 7.0 |
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Particle size
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95.0% min through 40mesh |
| Water |
5.0% max |
| Ash |
0.2% max |
| SO2 |
40mg/kg max |
| As |
0.5mg/kg max |
| Pb |
0.5mg/kg max |
| Cu |
5.0mg/kg max |
| Total plate count |
1000cfu/g max |
| Yeast |
25CFU/g max |
| Moulds |
25CFU/g max |
| E. colli |
30MPN/100g max |
| Pathogenic bacteria /25g (Salnonella SP., Staphylococcus aureus, Shigella spp.) |
Not detected |
| Taste & Odor |
Sweet taste, no odor |
| Foreign materials |
None |
| A |
White or pale yellow powder |
Please feel free to ask for a recent CoA of Fructo oligosaccharide (FOS) [308066-66-2]. Trigger the business.
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Pharma Sources Insight June 2024: Globalization on the Go
