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Sinoway Industrial Co.Ltd.
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Cefuroxime is the second-generation broad-spectrum semi-synthetic cephalosporin, and it has almost all antibacterial effects on all strains that are sensitive to cefalotin and ceftazidime, and it is also effective against a wide range of gram-negative bacilli including enterobacteriaceae and sputum Proteus is effective. Cefuroxime clinical treatment of respiratory tract, facial features, bone, soft tissue infections and meningitis, simple urinary tract infection clinical and bacteriological effective rate of 70% to 100%, prevention of postoperative wound infection also has a satisfactory effect. Cefuroxime is effective in the treatment of acute gonorrhea and urinary tract infections caused by gonococcal infection. A hospital in 169 cases of gonorrhea patients, intramuscular injection of cefuroxime a single dose of 1.5g, 160 cases of intramuscular injection disappeared in 1 to 5 days, the cure rate was 97.7%, short-term and long-term bacteriological cure rate of cefuroxime 55% and 48% .
| Items |
Specification |
Results |
| Appearance |
A White or almost white powder |
Complies |
| Identification |
IR spectrum exhibit maxima at the same wave numbers as the reference standard spectrum. |
Complies |
| Crystallinity |
Do not show birefringence or exhibit extinction position. |
Complies |
| Loss on drying |
≤1.3% |
0.69% |
| Diasetereoisomer ratio |
0.48 – 0.55 |
0.52 |
| Heavy metals |
≤ 20 ppm |
< 20ppm |
| Assay |
745 – 875 ug/mg |
818 ug/mg |
| Conclusiion |
This product complied with the standard of USP 36 |
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Lewoo Pharmatech(Shanghai)Co.,Ltd
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(6r,7r)-3-[[(aminocarbonyl)oxy]methyl]-7-[[(2e)-2-(2-furanyl)-2-(methoxyimino)-1-oxoethyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CEFUROXIME
CEFUROXIME ACID
(6r-(6-alpha,7-beta(z)))-e
1-(acetyloxy)ethylest
cxm-ax
sn407
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-(((aminocarbonyl)oxy)methyl)-7-((2-furanyl(methoxyimino)a cetyl)-amino)-8-oxo-, 1-(acetyloxy)ethyl ester, (6R-(6alpha,7beta(Z)))-
Axoril
CCI 15641
Ceftin
Cefurax
Cefuroxime 1-Acetoxymethyl Ester
Cefuroxine 1-acetoxyethyl ester
Cepazine
Elobact
Kefurox
Oraxim
Ximos
Zinnat |
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Pharma Sources Insight June 2024: Globalization on the Go
