PROSPER PHARMACHEM CO., LIMITED
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Tiamulin Hydrogen Fumarate,CAS NO 55297-96-6,C28H47NO4S.C4H4O4
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R&P PHARMACHEM (Righteous & Prosperous Pharmachem Co., Limited) has been specially engaged in the distribution of APIs, ingredients for feed and animal health/nutrition and ingredients for foodstuffs for many years.To source and acquire the products required by our clients from the best suppliers in China; to develop the markets that our suppliers are interested in by using our global network. In doing so, we aim to earn the trust and understanding necessary to build long-term working partnerships. Contact us: info(at)rppharmachem.com
The below list includes but not be limited to our strong products:
1. NEOMYCIN SULPHATE
2. Thiamine Mononitrate/Vitamin B1 Mono
3. Thiamine Hydrochloride/Vitamin B1 HCL
4. Halquinol
5. Inositol
6. Tiamulin Hydrogen Famarate
7. Chlortetracycline HCL
8. Sodium Saccharin
9. L-Tryptophan
10. Norfloxacin Base/Hcl
11. Doxycycline Hyclate
12. Nicarbazin
13. Zinc Bacitracin 10%/15% Powder/Granular
14. Tylosin Tartrate
15. Colistin Sulphate
16. Oxytetracycline Feed Grade 20%
17. Vitamin B6 HCL
18. Dextrose Anhydrous/Mono
19. BMD 11% Granular/Powder
20. VC coated 97%/VC mono 35%
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Shandong Shengli Bioengineering
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(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopentacycloocten-8-yl[[2-(diethylamino)ethyl]sulphayl]acetate hydrogen (E)-butenedioate.
- Chemical abstract service (CAS) registry number: 55297-96-6
- Molecular formula: C28H47NO4S·C4H4O4
- Relative molecular mass: 609.82
- Appearance: White or almost white crystal powder.
- Solubility: Soluble in water, freely soluble in anhydrous ethanol and soluble in methanol.
- Melting temperature: Between 143°C and 152°C.
- pH: A 1% solution (g/ml) in water has a pH of 3.1 to 4.1.
- Packaging and storage
Preserve in tight, light-resistant containers, and store at room temperature.
- Pharmacological properties
Tiamulin fumarate is a semi-synthetic diterpene antibiotic. The mode of action is by inhibition of ribosomal protein synthesis in sensitive bacteria. It is a bacteriostatic antibiotic and the following organisms show sensitivity in vitro:
Brachyspira: Brachyspira hyodysenteriae, Brachyspira pilosicoli
Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M. hyosynoviae, Ureaplasma spp.
Gram-positive: Staphylococcus spp., Streptococcus spp., Corynebacterium pyogenes.
Gram-negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis.
Following oral administration, tiamulin fumarate is rapidly absorbed and peak serum concentrations are achieved 2~4 hours after administration and concentrates in some tissues e.g. lung. Following absorption, it is rapidly metabolized and excreted.
For the treatment of chronic respiratory disease in chicken, the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium and Bacteroides spp. As an aid in the control of the enzootic pneumonia complex in pigs.
Mix with feed or water:
For pig: Every 1000kg feed, 40~100g Tiamulin fumarate, for 5~10 days consecutively.
For Chicken: Every 1L water, 125~250mg Tiamulin fumarate, for 5 days consecutively.
- Withdrawal period: 7 days for pig; 5 days for chicken.
- Contra-indications
Animals should not receive products containing monensin, narasin or salinomycin, during or for at least seven days before or after treatment with tiamulin.
Shelf life: 5 years.
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