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Sinoway Industrial Co.Ltd.
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Product name
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Budesonide
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CAS No.
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51333-22-3
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Molecular Formula
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C25H34O6
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Molecular Weight
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430.534
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Quality Standard
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97.5% up by HPLC, EP8/GMP/DMF
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Appearance
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White powder
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ITEMS
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STANDARDS
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RESULTS
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Appearance
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White or almost white crystalline powder
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Almost white crystalline powder
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Related substance
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A≤0.2%
D≤0.2%
K≤0.2%
L≤0.2%
Total impurities≤0.5%
Unspecified impurities≤0.1%
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0.02%
N.D.
N.D.
0.18%
0.34%
0.07%
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Epimer A
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40.0%~51.0%
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47.0%
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Residual solvents
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Methanol≤3000ppm
Acetonitril≤410ppm
Methylene Chloride≤600ppm
Ethanol≤5000ppm
Acetone≤5000ppm
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N.D.
N.D.
26ppm.
656ppm
N.D.
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Loss on drying
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≤0.5%
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0.14%
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Assay
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97.5%~102.0%
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99.3%
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Particle Size
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----
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99.3% 7.1μm
90.0% 4.6μm
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Conclusion
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Complies with the requirements of EP8.0
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Function of Budesonide
1. Budesonide can suppress the immune response that occurs when asthma occurs
2. Reduce the irritation response of the airway
3. Relieve bronchial obstruction caused by allergic reactions
4. Contraction and expansion of mucosal blood vessels, reducing blood vessel tension
5. The role of fighting inflammation, especially chronic inflammation
6. Relieve asthma and breathing difficulties
7. Improve lung ventilation function
8. Effectively prevent asthma in adults and children
9. Pathological symptoms such as airway mucosal edema and thickening of epithelial basement membrane caused by chronic asthma
Budesonide is often used for nebulization treatment. The patient can inhale budesonide suspension to reduce phlegm and expectorant, relieve spasm and relieve asthma. In fact, nebulization is commonly used in respiratory and pediatrics, and the main population is the elderly and infants with poor sputum expectoration ability. |
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