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Xi’an Natural Field Bio-Technique Co., Ltd
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10 DAB III,10-Deacetyl Baccatin III,10-dab
Product Description
| Basic Information |
| Product Name |
10 DAB III,10-Deacetyl Baccatin III,10-dab |
| Botanical Source |
Taxus Baccata |
| Active Ingredient |
10DAB 99% by HPLC |
| Appearance |
White Crystalline Powder |
| Molecular Formula |
C29H36O10 |
| Molecular Weight |
544.597 |
| CAS |
32981-96-5 |
| Packing |
| 25kg/drum or according to customers' requirements for 10-DAB-III |
| Storage |
| Store in cool & dry place, keep away from strong light and heat |
| Shelf life |
| 24 months when properly stored |
What is 10-Deacetyl Baccatin III or 10-DAB-III?It is a natural organic compound isolated from the Pacific yew tree (Taxus) and related species.10-DAB III is a white to off white crystalline powder, insoluble in water.
10-Deacetyl Baccatin III or 10-DAB III is a crucial intermediate for Docitaxel, two of the best anti-cancer drugs ever invented. By extracting the pre-cursor 10-DAB III in large quantites from the Taxus baccata leaf, many subsequent semiayntheses can be carried out. The esterification of 10-DAB III also causes an enhancement in the kinetics, and therefore the pharmacological profile of these important chemo-therapeutic agents.
Applications:
-Anti-cancer active Drug Substance
Packing and Shipping
  
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SHANXI YONGJIN GROUP CO LTD
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Product Name：10-Deacetylbaccatin III
Other Name:(2α,5β,7β,10α,13α)-4-Acetoxy-1,7,10,13-tetrahydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate丨Docetaxel impurity E丨DESACETYLBACCATINE丨10DBA III
Molecular Formula：C29H36O10
Molecular Weight：544.590
Use：10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. IC50 value:Target: Taxols have exhibit antitumor agents. Several of these taxols can be synthesized from 10- Deacetylbaccatin-III. 10-Deacetylbaccine III is the fifth intermediate of paclitaxel biosynthesis. The biosynthetic pathway consists of approximately 20 enzymatic steps but is not fully elucidated. 10-Deacetylbaccine III is an antineoplastic agent and an anti-cancer intermediate.
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