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Synvent Materials Corporation
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1, suitable for wet and dry granulation, direct pressing and coating, hot melt extrusion and other processes
2, highly crosslinked network structure, with capillary effect and expansion effect, suitable for a variety of disintegrating prescriptions, can meet the requirements of different acid and base prescriptions
3, as a super disintegrant, can promote the release of active substances in tablets, capsules and granules, improve dissolution and bioavailability
4, as an adsorbent and complexing agent, improve the dissolution and bioavailability of insoluble drugs
5. As a masking agent, it can cover the odor of substances such as acetaminic acid and azithromycin
6, strong compressibility, reduce the brittleness, improve the hardness of the tablet |
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Zhejiang Retron Biotech Co., Ltd.
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Cross-linked povidone is a white or off-white free-flowing powder, no special odor, insoluble in water, acid, alkali and commonly used solvents. It can be used as a super disintegrant, because it has strong swelling power in water and does not form a gel after expansion, which can effectively improve the dissolution and bioavailability of drugs, so it is considered to be the preferred disintegrant for high-grade tablets, especially suitable for the formulation of instant and chewable tablets. It can also be used as an adsorbent and complexing agent, because it has very good co-solubility, can be complexed with polyphenols, carboxylic acids, tannins and small molecules, and can stabilize the active ingredients of drugs through complexation, and improve drug release and bioavailability. It can also be used as a suspension stabilizer to reduce the sedimentation of drug particles and increase the redispersion capacity of sedimented liquids. |
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Pharma Sources Insight January 2025
