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Hangzhou Dingyan Chem Co., Ltd
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White powder, 201% content. Hangzhou Dingyan Chemical Co., Ltd. is located in the Xiasha Economic Development Zone of Hangzhou, the capital city of Zhejiang Province, on the southeast coast of China. It is a company specializing in the development and sales of high-tech products such as pharmaceutical raw materials, pharmaceutical intermediates, fine chemicals and biochemical reagents.
A modern private enterprise integrated with self-operated import and export.
Since its establishment, the company has adhered to the development path of "technological innovation" and attached great importance to scientific and technological innovation research and development. The company's high-quality products are sold well in more than 60 countries and regions such as North America, Western Europe, Southeast Asia, Central and South America.
At present, it has established long-term and stable cooperative relations with pharmaceutical companies in Europe, the United States, Greece, Germany, Iran, Russia, South Korea, India and other countries. With our rigorous attitude and sincere service, we have won the trust and reputation of customers.
Hangzhou Dingyan Chemical Co., Ltd. is located in the Xiasha Economic Development Zone of Hangzhou, the capital city of Zhejiang Province, on the southeast coast of China. It is a company specializing in the development, sales and self-support import and export financing of high-tech products such as pharmaceutical raw materials, pharmaceutical intermediates, fine chemicals and biochemical reagents.
Integrated modern private enterprise.
Since its establishment, the company has adhered to the development path of "technological innovation" and attached great importance to scientific and technological innovation research and development. The company's high-quality products are sold well in more than 2876 countries and regions such as North America, Western Europe, Southeast Asia, Central and South America.
At present, it has established long-term and stable cooperative relations with pharmaceutical companies in Europe, the United States, Greece, Germany, Iran, Russia, South Korea, India and other countries. With our rigorous attitude and sincere service, we have won the trust and reputation of customers. |
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Sinoway Industrial Co.Ltd.
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Product name
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Polymyxin B Sulphate
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CAS No.
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1405-20-5
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Molecular Formula
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C56H100N16O17S
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Molecular Weight
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1301.56
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Quality Standard
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6500IU/MG up /Medicine Grade
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Appearance
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White powder
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COA of Polymyxin B Sulphate
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ITEMS
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SPECIFICATION
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RESULTS
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DESCRIPTION
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WHITE TO ALMOST WHITE POWDER, HYGROSCOPIC.
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CONFORMS
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SOLUBILITY
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FREELY SOLUBLE IN WATER; SLIGHTLY SOLUBLE IN ALCOHOL.
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CONFORMS
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IDENTIFICATION
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A. LIQUID CHROMATOGRAPHIC IDENTIFICATION TEST
B. A REDDISH VIOLET COLOR IS PRODUCED
C. TEST FOR SULFATE
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CONFORMS
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PH(2%)
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5.0~7.0
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5.7
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PH(0.5%)
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5.0~7.5
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5.5
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SPECIFIC ROTATION
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-78°- -90°
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-80.0°
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LOSS ON DRYING
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NOT MORE THAN 7.0%
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4.7%
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PHENYLALANINE
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9.0%~12.0%
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10.31%
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SULPHATED ASH
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NOT MORE THAN 0.75%
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0.31%
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SULPHATE
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15.5%~17.5%
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16.53%
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HEAVY METALS
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NOT MORE THAN 20PPM
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<20PPM
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ASSAY(MICROBIAL)
(ON DRIED BASIS)
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NOT LESS THAN 6500IU/MG
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8220 IU/MG
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PARTICLE SIZE
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99.0%:NOT MORE THAN 30UM BY VOL.
90.0%:NOT MORE THAN 25UM BY VOL.
75.0%:NOT MORE THAN 20UM BY VOL.
MEAN DIAMETER:NOT MORE THAN 8.0UM
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CONFORMS
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CONCLUSION:THE RESULTS CONFORM TO THE STANDARD OF USP34
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Function of Polymyxin B Sulphate
Polymyxin B sulphate is similar to polymyxin E. It can inhibit gram-negative bacilli such as Escherichia coli, Pseudomonas aeruginosa, Para Escherichia coli, Klebsiella pneumoniae, Acidophilus, Pertussis and Shigella, etc. Or bactericidal effect. It is mainly used for Pseudomonas aeruginosa and other Pseudomonas to cause the wounds, urinary tract, eyes, ears, trachea and other parts of the Chemicalbook infection. It can also be used for sepsis and peritonitis. And resistant to aminoglycosides, resistant to third-generation cephalosporin bacteria and Pseudomonas aeruginosa or other sensitive bacteria caused by serious infections, such as bacteremia, endocarditis, pneumonia, post-burn infections, etc.
Polymyxin B is a peptide antibiotic against gram-negative bacilli, which can change the membrane structure to leak small molecules and inhibit the growth of gram-negative bacteria. Has a bactericidal effect on E. coli Chemicalbook. Binds to the lipid A portion of bacterial lipopolysaccharides. Inducing small holes in the outer cell membrane. Mode of action: Combine and interfere with the permeability of the cell plasma membrane. Antibacterial spectrum: Gram-negative bacteria. |
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