Lifecome Biochemistry Co., Ltd.
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Colistin is a polypeptide antibiotic belonging to the polymyxin class. Colistin exerts a bactericidal action on susceptible bacteria strains by disruption of the bacteria cytoplasmic membrane leading to an alteration of cell permeability and then a leakage of intracellular materials. Colistin is bactericidal and is primarily effective against a range of gram negative bacteria, such as enterobacteriaceae and in particular Escherichia coli. Colistin possesses virtually no activity against gram-positive bacteria and fungi.
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