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Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
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The product is an intermediate of medicine and pesticides. It is used in the production of dicoumarin, neoanticoagulant, warfarin and other anticoagulant drugs. These 4-hydroxycoumarin derivatives are a class of oral anticoagulants. Due to irregular and incomplete absorption, dicoumarin has been replaced by warfarin and the like. Dicoumarin lasts the longest (4-7 days), warfarin longer (3-5 days), neocoagulation is shorter (2-4 days), and coumarin ethyl ester is the shortest (2-3 days). 4-Hydroxycoumarin is also an intermediate of some rodenticides, such as raticide, chlorcidal chemicalbook, gram rodenticide, raticide, biphenyl raticidal naphthalene, etc. Funcide is the first generation of anticoagulant rodenticides, widely used all over the world, and the effect of raticidal is very good. The second-generation anticoagulant rodenticide is bromobiphenyl rodenticide, which can poison rats to death with a single bait, and has accounted for 30% of the rodenticide market in the United States. 4-Hydroxycoumarins are also a spice, and coumarins are widely distributed in the plant kingdom. Cows and horses eating spoiled alfalfa have died of bleeding due to loss of hemocoagulability, which may be caused by the formation of dicoumarin in the plant. |
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Pharma Sources Insight January 2025
