Han Traceability(Shaanxi) Biological Technology Co.,Ltd
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Epigallocatechin gallate (EGCG) is a unique plant compound thought to reduce inflammation, aid weight loss, and help prevent heart and brain disease.
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Han Traceability(Shaanxi) Biological Technology Co.,Ltd
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Common Name: Epigallocatechin gallate
Molecular Formula: C11H12N2O3
Molecular Weight: 220.225
CAS: 989-51-5
Epigallocatechin Gallate (EGCG) inhibits activation EGFR, HER2 and HER3 in the SW837 human colon cancer cell line. (-)-Epigallocatechin Gallate (10 μM) also inhibits cell growth, suppresses activation of EGFR, HER2, and HER3, and causes decrease in the levels of COX-2 and Bcl-xL proteins, and apoptosis after treatment for 96 h[1]. (-)-Epigallocatechin Gallate (0-35 μg/mL) inhibits the proliferation of colorectal cancer cells. (-)-Epigallocatechin Gallate (35 μg/mL) induces apoptosis of colorectal cancer cells[2]. (-)-Epigallocatechin Gallate (EGCG; 50, 75 and 100 μM) dose-dependently inhibits the growth of HepG2 cells, and induces apoptosis in HepG2 cells[3]. |
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