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Sinoway Industrial Co.Ltd.
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Product Information
| Product Name |
Levonorgestrel |
| CAS. |
797-63-7 |
| Molecular Weight |
312.45 |
| Molecular Formula |
C21H28O2 |
| EINECS |
212-349-8 |
| Melting point |
206°C |
| Boiling point |
392.36°C (rough estimate) |
Description
Levonorgestrel is a synthetic progestational hormone with actions similar to those of progesterone and about twice as potent as its racemic or[+-]-isomer[norgestrel][1]. It is a kind of emergency contraception, referring as a drug or device used to prevent pregnancy after unprotected sexual intercourse[including sexual assault] or after a recognized contraceptive failure. It is used for contraception, control of menstrual disorders, and treatment of endometriosis. Levonorgestrel is marketed mostly as a combination oral contraceptive under several brand names such as Alesse, Triphasil, and Min-Ovral. It is also marketed under the brand of Plan B.
Levonorgestrel was discovered in 1963 and was introduced for medical use together with ethinylestradiol in 1970.[2, 3] It is listed as an essential medicine by the World Health Organization, being the most effective and safe medicines needed in a health system. It is available as a generic medication.
Levonorgestrel is a levo-isomer of Norgestrel. The progestins include the naturally occurring hormone progesterone, 17a-acetoxyprogesterone derivatives in the pregnane series, 19-nortestosterone derivatives(estranes), and norgestrel and related compounds in the gonane series. The 19-nortestosterone derivatives were developed for use as progestins in oral contraceptives, and while their predominant activity is progestational, they exhibit androgenic and other activities. The gonanes are a more recently developed series of "19-nor" compounds, containing an ethyl rather than a methyl substituent in the 13-position, and they have diminished androgenic activity.
Usage
Levonorgestrel is used by women to prevent pregnancy after birth control failure (such as a broken condom) or unprotected sex. This medication is an emergency contraceptive and should not be used as a regular form of birth control. It is a progestin hormone that works mainly by preventing the release of an egg (ovulation) during your menstrual cycle. It also makes vaginal fluid thicker to help prevent sperm from reaching an egg (fertilization) and changes the lining of the uterus (womb) to prevent attachment of a fertilized egg.
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