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Home > CAS No. Inquiry > 520-27-4

520-27-4

[CAS Name] Diosmin

[Formula] C28H32O15

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Basica Info

[CAS Name]Diosmin
[Alias]3',5,7-trihydroxy-4'-methoxyflavone 7-rutinoside; 3,5,7-Trihydroxy-4-methoxyflavone-7- rutinoside; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranoside; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxyhexopyranosyl)hexopyranoside; 5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-oxo-4H-chromen-7-yl 6-O-(6-deoxy-alpha-D-mannopyranosyl)-beta-D-glucopyranoside
[Number]520-27-4
[EINECS]208-289-7
[Formula]C28H32O15
[Molecular weight]608.5447

[Boiling point]926.8°C at 760 mmHg
[Density]0mmHg at 25°C
[Flash point]305.2°C

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Main Products

SHANGHAI PASSIONO INT'L CO., LTD.

Product name:Diosmin

Spec:EP6 90%, 92%, 95%;diosmin/hesperidin(9:1);non-micronized, micronized

Latin name: Citrus Auranti

Specification available:8%-98%

CAS NO:520-27-4

Molecular formulaC₂₈H₃₂O₁₅

Packing size:25kg/Drum

Delivery:Prompt

OEM service:

Offered tablets capsule with bottle.

Description

1.Diosmin is a biogenic amine derived by extracting hesperidin from Citrus Aurantium L., followed by conversion of hesperidin to diosmin.

2.Diosmin is considered to be a vascular-protecting agent used to treat chronic venous insufficiency, hemorrhoids, lymphedema, and varicose veins.

3.As a flavonoid, diosmin also exhibits anti-inflammatory, free-radical scavenging, and antimutagenic properties.

4.Diosmin has been used for more than 30 years as a phlebotonic and vascular-protecting agent, and has recently begun to be investigated for other therapeutic purposes, including cancer, premenstrual syndrome, colitis, and diabetes.

Appearance

Greyish-yellow or light yellow hygroscopic powder.

Solubility

Practically insoluble in water, soluble in dimethyl sulphoxide, practically insoluble in alcohol. It dissolves in dilute solutions of alkali hydroxides

Identification and test for Iodine and related substances by IR, HPLC according to EP6.0

Standard controls of Microbiology, Loss on drying, Heavy metals according to EP

Residual solvents (ethnol, ethanol and prydine) meets ICH guidline

Storage - in an airtight container

Shelf life - 2 years.

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SHAANXI GUANJIE TECHNOLOGY CO., LTD

Brief Introduction

Diosmin is a flavonoid derivative, for the treatment of bad microcirculation, edema formation of lymphatic function and capillary filtration, brittle and permeability of regulation, and to increase vascular permeability and reduce the capillary resistance. Also it can be used for hemorrhoids, chronic venous insufficiency, lymphatic venous insufficiency related symptons (heavy legs, pain, discomfort and ache in the morning), as well as the acute hemorrhoids symptoms.

Detailed Product Description

Product name: Diosmin

Latin name:Citrus Aurantium L.

Active ingredient:Diosmin

Specification:25% 98%

CAS NO. : 520-27-4

Appearance:Yellowish brown powder to Almost white powder

Molecular weight:608.55

Molecular formula:C28H32O15

Usage: Pharmaceuticals, healthcares,and cosmetics

Main Functions

Diosmin is used for treating various disorders of blood vessels including hemorrhoids, varicose veins, poor circulation in the legs (venous stasis), and bleeding (hemorrhage) in the eye or gums. 2.It is also used to treat swelling of the arms (lymphedema) following breast cancer surgery, and to protect against liver toxicity.

3.It is often taken in combination with hesperidin, another plant chemical.

Packing &Storage Condition

Storage: Store in cool & dry place, Keep away from strong light and heat.

Shelf life: 24Months when properly stored.

Packing: 25/kg paper drum and two plastic-bags inside

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Changsha Staherb Natural Ingredients Co., Ltd.

CAS:	520-27-4
MF:	C28H32O15
MW:	608.54

1, Has specific affinity to the venous system, enhance the tension system without affecting the artery of vein;
2, To the microcirculation system, decrease the blood viscosity, improve the velocity of reducing silt up;
3, Contract the lymphatic system, which can enhance lymphatic and lymph drainage speed, speed up the return relieve edema.
4, Commercially available diosmin uses micronization technology, increase the contact area after using medicine, absorb more and higher bioavailability. Suitable for all kinds of hemorrhoids and acute hemorrhoids, also can be used for the treatment of chronic venous insufficiency, such as varicose veins, leg ulcers, etc.

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